Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   RDV59_RS05985 Genome accession   NZ_CP133476
Coordinates   1191826..1192533 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain LMG 11489     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1186826..1197533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV59_RS05960 (RDV59_05960) - 1187585..1188352 (-) 768 WP_060775856.1 amino acid ABC transporter ATP-binding protein -
  RDV59_RS05965 (RDV59_05965) - 1188538..1189188 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  RDV59_RS05970 (RDV59_05970) - 1189200..1189898 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  RDV59_RS05975 (RDV59_05975) - 1189916..1190749 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  RDV59_RS05980 (RDV59_05980) - 1190759..1191526 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  RDV59_RS05985 (RDV59_05985) vicR 1191826..1192533 (+) 708 WP_002884978.1 response regulator YycF Regulator
  RDV59_RS05990 (RDV59_05990) vicK 1192526..1193869 (+) 1344 WP_038675887.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RDV59_RS05995 (RDV59_05995) vicX 1193875..1194684 (+) 810 WP_126405093.1 MBL fold metallo-hydrolase Regulator
  RDV59_RS06000 (RDV59_06000) - 1194743..1195102 (+) 360 WP_037611660.1 YbaN family protein -
  RDV59_RS06005 (RDV59_06005) - 1195154..1196368 (-) 1215 WP_038675892.1 aminoacyltransferase -
  RDV59_RS06010 (RDV59_06010) yidA 1196370..1197179 (-) 810 WP_002890845.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=874670 RDV59_RS05985 WP_002884978.1 1191826..1192533(+) (vicR) [Streptococcus salivarius strain LMG 11489]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=874670 RDV59_RS05985 WP_002884978.1 1191826..1192533(+) (vicR) [Streptococcus salivarius strain LMG 11489]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCGATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACCTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387