Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLA22_RS10635 Genome accession   NZ_CP128421
Coordinates   2090490..2091713 (+) Length   407 a.a.
NCBI ID   WP_015082939.1    Uniprot ID   A0AAJ6N3N8
Organism   Lactococcus cremoris strain A.2.2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2085490..2096713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLA22_RS10610 (LLA22_10665) - 2086605..2087408 (-) 804 WP_015082937.1 phosphatidate cytidylyltransferase -
  LLA22_RS10615 (LLA22_10670) - 2087408..2088142 (-) 735 WP_011836054.1 isoprenyl transferase -
  LLA22_RS10620 (LLA22_10675) yajC 2088492..2088824 (-) 333 WP_015082938.1 preprotein translocase subunit YajC -
  LLA22_RS10625 (LLA22_10680) - 2088919..2089608 (-) 690 Protein_2066 DNA alkylation repair protein -
  LLA22_RS10630 (LLA22_10685) rlmH 2089635..2090114 (-) 480 WP_011677194.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLA22_RS10635 (LLA22_10690) htrA 2090490..2091713 (+) 1224 WP_015082939.1 S1C family serine protease Regulator
  LLA22_RS10640 (LLA22_10695) - 2091835..2092833 (+) 999 WP_014573349.1 glycosyltransferase family 4 protein -
  LLA22_RS10645 (LLA22_10700) - 2092971..2094311 (+) 1341 WP_015082940.1 glycosyltransferase family 4 protein -
  LLA22_RS10650 (LLA22_10705) - 2094419..2094643 (+) 225 WP_011677198.1 YkuJ family protein -
  LLA22_RS10655 (LLA22_10710) - 2094787..2095791 (+) 1005 WP_081213198.1 hypothetical protein -
  LLA22_RS10660 (LLA22_10715) - 2095848..2096600 (-) 753 WP_014573352.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41468.93 Da        Isoelectric Point: 5.7690

>NTDB_id=847449 LLA22_RS10635 WP_015082939.1 2090490..2091713(+) (htrA) [Lactococcus cremoris strain A.2.2]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSGGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=847449 LLA22_RS10635 WP_015082939.1 2090490..2091713(+) (htrA) [Lactococcus cremoris strain A.2.2]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGGGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(295-391)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

Peptidase family M50 (Peptidase_M50)

(234-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.872

95.823

0.526
  htrA Streptococcus mitis NCTC 12261

55.614

94.103

0.523
  htrA Streptococcus pneumoniae R6

57.849

84.521

0.489
  htrA Streptococcus pneumoniae TIGR4

57.849

84.521

0.489
  htrA Streptococcus pneumoniae D39

57.849

84.521

0.489
  htrA Streptococcus pneumoniae Rx1

57.849

84.521

0.489
  htrA Streptococcus mutans UA159

53.117

90.663

0.482