Detailed information NTG0809528

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: P6F23_RS00410
• Genome accession: NZ_CP120953
• Coordinates: 64134..65036 (+)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain GBSIR0001
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 59134..70036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P6F23_RS00385 (P6F23_00385)	purE	59310..59801 (+)	492	WP_001875905.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
P6F23_RS00390 (P6F23_00390)	purK	59788..60861 (+)	1074	WP_001048172.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
P6F23_RS00395 (P6F23_00395)	-	60871..61128 (+)	258	WP_000590468.1	hypothetical protein	-
P6F23_RS00400 (P6F23_00400)	-	61494..62597 (+)	1104	WP_001867169.1	DUF6287 domain-containing protein	-
P6F23_RS00405 (P6F23_00405)	purB	62683..63981 (+)	1299	WP_000893937.1	adenylosuccinate lyase	-
P6F23_RS00410 (P6F23_00410)	comR	64134..65036 (+)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
P6F23_RS00415 (P6F23_00415)	ruvB	65325..66323 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
P6F23_RS00420 (P6F23_00420)	-	66475..66912 (+)	438	WP_000754817.1	low molecular weight protein-tyrosine-phosphatase	-
P6F23_RS00425 (P6F23_00425)	-	66919..67299 (+)	381	WP_000787702.1	membrane protein	-
P6F23_RS00430 (P6F23_00430)	-	67296..69074 (+)	1779	WP_001220911.1	acyltransferase family protein	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=809528 P6F23_RS00410 WP_000912098.1 64134..65036(+) (comR) [Streptococcus agalactiae strain GBSIR0001]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=809528 P6F23_RS00410 WP_000912098.1 64134..65036(+) (comR) [Streptococcus agalactiae strain GBSIR0001]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367