Detailed information NTG0782799

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: PO847_RS18245
• Genome accession: NZ_CP117197
• Coordinates: 3654723..3655886 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain 3ZT
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3649723..3660886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PO847_RS18215 (PO847_18215)	-	3649988..3650407 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
PO847_RS18220 (PO847_18220)	comFC	3650481..3651170 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
PO847_RS18225 (PO847_18225)	-	3651176..3651460 (-)	285	WP_022553866.1	competence protein ComFB	-
PO847_RS18230 (PO847_18230)	comFA	3651518..3652903 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
PO847_RS18235 (PO847_18235)	-	3653011..3653859 (-)	849	WP_003151387.1	DegV family protein	-
PO847_RS18240 (PO847_18240)	degU	3653957..3654646 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
PO847_RS18245 (PO847_18245)	degS	3654723..3655886 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
PO847_RS18250 (PO847_18250)	-	3656109..3656756 (+)	648	WP_007407485.1	YigZ family protein	-
PO847_RS18255 (PO847_18255)	-	3656761..3657975 (+)	1215	WP_022553868.1	LCP family protein	-
PO847_RS18260 (PO847_18260)	-	3658075..3659151 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
PO847_RS18265 (PO847_18265)	-	3659283..3660479 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=782799 PO847_RS18245 WP_007407484.1 3654723..3655886(-) (degS) [Bacillus velezensis strain 3ZT]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=782799 PO847_RS18245 WP_007407484.1 3654723..3655886(-) (degS) [Bacillus velezensis strain 3ZT]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951