Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | GDK21_RS00310 | Genome accession | NZ_AP019542 |
| Coordinates | 62941..64569 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain KG-03 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57720..102777 | 62941..64569 | within | 0 |
| SCCmec | 44575..65940 | 62941..64569 | within | 0 |
Gene organization within MGE regions
Location: 44575..102777
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GDK21_RS00200 (SAKG03_00390) | mecA | 44575..46584 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| GDK21_RS00205 (SAKG03_00400) | mecR1 | 46681..48438 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| GDK21_RS00210 (SAKG03_00410) | mecI | 48438..48809 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| GDK21_RS00215 | psm-mec | 48894..48962 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| GDK21_RS00220 (SAKG03_00420) | - | 49296..50426 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| GDK21_RS00225 (SAKG03_00440) | cstB | 50540..51874 (-) | 1335 | Protein_40 | persulfide dioxygenase-sulfurtransferase CstB | - |
| GDK21_RS00230 (SAKG03_00450) | - | 51907..52971 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| GDK21_RS00235 (SAKG03_00460) | cstR | 53107..53367 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| GDK21_RS00240 (SAKG03_00470) | - | 53367..54005 (+) | 639 | Protein_43 | sulfite exporter TauE/SafE family protein | - |
| GDK21_RS00250 (SAKG03_00480) | - | 54350..55012 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| GDK21_RS00265 (SAKG03_00490) | erm(A) | 55546..56277 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| GDK21_RS00270 (SAKG03_00500) | - | 56403..57185 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| GDK21_RS00275 (SAKG03_00510) | - | 57336..57713 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| GDK21_RS00280 (SAKG03_00520) | - | 57720..59612 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| GDK21_RS00285 (SAKG03_00530) | - | 59609..60694 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| GDK21_RS00290 (SAKG03_00540) | - | 60813..61130 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| GDK21_RS00295 (SAKG03_00550) | - | 61151..61657 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| GDK21_RS00300 (SAKG03_00560) | - | 61675..61986 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| GDK21_RS00305 (SAKG03_00570) | - | 62073..62423 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| GDK21_RS00310 (SAKG03_00580) | ccrB | 62941..64569 (-) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| GDK21_RS00315 (SAKG03_00590) | ccrA | 64591..65940 (-) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| GDK21_RS00320 (SAKG03_00600) | - | 66174..67967 (-) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| GDK21_RS00325 (SAKG03_00610) | - | 67967..68263 (-) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| GDK21_RS00330 (SAKG03_00620) | - | 68456..69502 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| GDK21_RS00335 | - | 69753..70894 (-) | 1142 | Protein_59 | IS3-like element ISSau4 family transposase | - |
| GDK21_RS00340 (SAKG03_00660) | - | 71501..72673 (+) | 1173 | WP_000195429.1 | IS256-like element IS256 family transposase | - |
| GDK21_RS00345 (SAKG03_00670) | - | 72737..73663 (-) | 927 | Protein_61 | YfcC family protein | - |
| GDK21_RS00350 (SAKG03_00680) | - | 74385..75080 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| GDK21_RS00355 (SAKG03_00690) | - | 75055..77724 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| GDK21_RS00360 | kdpF | 77891..77971 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| GDK21_RS00365 (SAKG03_00710) | kdpA | 77992..79668 (+) | 1677 | WP_000029432.1 | potassium-transporting ATPase subunit KdpA | - |
| GDK21_RS00370 (SAKG03_00720) | - | 79687..81708 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| GDK21_RS00375 (SAKG03_00730) | - | 81724..82281 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| GDK21_RS00380 (SAKG03_00740) | - | 82826..83695 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| GDK21_RS00385 (SAKG03_00750) | - | 83705..84601 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| GDK21_RS00395 (SAKG03_00780) | - | 85720..86346 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| GDK21_RS00400 (SAKG03_00790) | - | 86461..87969 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| GDK21_RS00405 | - | 88219..88353 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| GDK21_RS00410 | - | 88317..88409 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| GDK21_RS00415 (SAKG03_00800) | - | 88556..90301 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| GDK21_RS00420 (SAKG03_00810) | - | 90399..90754 (-) | 356 | Protein_75 | tRNA-dihydrouridine synthase | - |
| GDK21_RS00425 | - | 91059..91147 (-) | 89 | Protein_76 | hypothetical protein | - |
| GDK21_RS00430 (SAKG03_00820) | - | 91245..92000 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| GDK21_RS00435 (SAKG03_00830) | cstR | 92000..92260 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| GDK21_RS00440 (SAKG03_00840) | cstA | 92397..93461 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| GDK21_RS00445 (SAKG03_00850) | cstB | 93492..94826 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| GDK21_RS00450 (SAKG03_00860) | sqr | 94845..96038 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| GDK21_RS15350 | - | 96305..96519 (-) | 215 | Protein_82 | universal stress protein | - |
| GDK21_RS00465 (SAKG03_00870) | - | 96705..97691 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| GDK21_RS00470 (SAKG03_00880) | - | 98000..98203 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| GDK21_RS00475 (SAKG03_00890) | - | 98252..98548 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| GDK21_RS00480 (SAKG03_00900) | - | 98756..99358 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| GDK21_RS00485 (SAKG03_00910) | - | 99625..102777 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=72711 GDK21_RS00310 WP_001186602.1 62941..64569(-) (ccrB) [Staphylococcus aureus strain KG-03]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=72711 GDK21_RS00310 WP_001186602.1 62941..64569(-) (ccrB) [Staphylococcus aureus strain KG-03]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |