Detailed information NTG0071700

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: D5070_RS14490
• Genome accession: NZ_AP018923
• Coordinates: 2759027..2759914 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain JMUB3031
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2754027..2764914

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5070_RS14455	-	2754046..2754138 (+)	93	WP_010956583.1	hypothetical protein	-
D5070_RS14460 (JMUB3031_2684)	-	2754246..2754743 (-)	498	WP_001065268.1	glutathione peroxidase	-
D5070_RS14465 (JMUB3031_2685)	-	2754753..2755013 (-)	261	WP_001791974.1	hypothetical protein	-
D5070_RS14475	-	2755395..2755508 (-)	114	Protein_2684	hypothetical protein	-
D5070_RS14480 (JMUB3031_2686)	-	2756167..2758167 (-)	2001	WP_000776740.1	ABC transporter permease	-
D5070_RS14485 (JMUB3031_2687)	-	2758164..2758919 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
D5070_RS14490 (JMUB3031_2688)	braS	2759027..2759914 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
D5070_RS14495 (JMUB3031_2689)	braR	2759925..2760590 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
D5070_RS14500 (JMUB3031_2690)	-	2760616..2760816 (-)	201	WP_000604727.1	hypothetical protein	-
D5070_RS14505 (JMUB3031_2691)	-	2761014..2762438 (+)	1425	WP_000953748.1	alkaline phosphatase	-
D5070_RS15410	-	2762498..2762599 (-)	102	WP_000731972.1	SE2200 family small protein	-
D5070_RS14515 (JMUB3031_2692)	-	2762721..2763176 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
D5070_RS14520 (JMUB3031_2694)	-	2763421..2764182 (-)	762	Protein_2693	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=71700 D5070_RS14490 WP_000143417.1 2759027..2759914(-) (braS) [Staphylococcus aureus strain JMUB3031]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=71700 D5070_RS14490 WP_000143417.1 2759027..2759914(-) (braS) [Staphylococcus aureus strain JMUB3031]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99