Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NMK49_RS09625 Genome accession   NZ_CP101124
Coordinates   1972179..1972904 (+) Length   241 a.a.
NCBI ID   WP_000688494.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967179..1977904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK49_RS09595 - 1967398..1968024 (+) 627 WP_000522384.1 nitroreductase family protein -
  NMK49_RS09600 - 1968385..1969170 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  NMK49_RS13280 - 1969767..1969901 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NMK49_RS09610 agrB 1970137..1970706 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  NMK49_RS09615 agrD 1970703..1970843 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NMK49_RS09620 agrC 1970868..1972160 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  NMK49_RS09625 agrA 1972179..1972904 (+) 726 WP_000688494.1 quorum-sensing response regulator AgrA Regulator
  NMK49_RS09630 - 1972968..1973075 (+) 108 WP_001790167.1 hypothetical protein -
  NMK49_RS09635 - 1973263..1974222 (-) 960 WP_001253312.1 carbohydrate kinase -
  NMK49_RS09640 - 1974219..1975703 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  NMK49_RS09645 - 1975852..1976802 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 28289.35 Da        Isoelectric Point: 6.3009

>NTDB_id=708887 NMK49_RS09625 WP_000688494.1 1972179..1972904(+) (agrA) [Staphylococcus aureus subsp. aureus RN4220]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKNII
R

Nucleotide


Download         Length: 726 bp        

>NTDB_id=708887 NMK49_RS09625 WP_000688494.1 1972179..1972904(+) (agrA) [Staphylococcus aureus subsp. aureus RN4220]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAATATAATA
AGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

98.34

0.983