Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NLY77_RS07230 Genome accession   NZ_CP100431
Coordinates   1434946..1435650 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain 1521251     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429946..1440650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS07215 (NLY77_07215) - 1431784..1432233 (-) 450 WP_043032937.1 ATP-binding cassette domain-containing protein -
  NLY77_RS07220 (NLY77_07220) vicX 1432794..1433597 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  NLY77_RS07225 (NLY77_07225) micB 1433604..1434953 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NLY77_RS07230 (NLY77_07230) micA 1434946..1435650 (-) 705 WP_002935840.1 response regulator YycF Regulator
  NLY77_RS07235 (NLY77_07235) - 1435844..1436605 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NLY77_RS07240 (NLY77_07240) - 1436616..1437455 (+) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  NLY77_RS07245 (NLY77_07245) - 1437470..1438168 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  NLY77_RS07250 (NLY77_07250) - 1438183..1438842 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=705268 NLY77_RS07230 WP_002935840.1 1434946..1435650(-) (micA) [Streptococcus suis strain 1521251]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=705268 NLY77_RS07230 WP_002935840.1 1434946..1435650(-) (micA) [Streptococcus suis strain 1521251]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376