Detailed information NTG0704290

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NKZ63_RS08810
• Genome accession: NZ_CP100326
• Coordinates: 1751738..1752787 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain STC90
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1746738..1757787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ63_RS08790 (NKZ63_08790)	trpB	1747054..1748229 (-)	1176	WP_204101559.1	tryptophan synthase subunit beta	-
NKZ63_RS08795 (NKZ63_08795)	-	1749264..1749791 (-)	528	WP_002942846.1	VanZ family protein	-
NKZ63_RS08800 (NKZ63_08800)	rlmN	1749788..1750900 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NKZ63_RS08805 (NKZ63_08805)	-	1750909..1751550 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
NKZ63_RS08810 (NKZ63_08810)	sepM	1751738..1752787 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NKZ63_RS08815 (NKZ63_08815)	coaD	1752774..1753262 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
NKZ63_RS08820 (NKZ63_08820)	rsmD	1753252..1753791 (-)	540	WP_024388284.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NKZ63_RS08825 (NKZ63_08825)	-	1754098..1754820 (-)	723	WP_044684680.1	hypothetical protein	-
NKZ63_RS08830 (NKZ63_08830)	-	1754877..1755263 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NKZ63_RS08835 (NKZ63_08835)	-	1755263..1755481 (-)	219	WP_041179287.1	YqgQ family protein	-
NKZ63_RS08840 (NKZ63_08840)	-	1755789..1756391 (-)	603	WP_015647237.1	response regulator transcription factor	-
NKZ63_RS08845 (NKZ63_08845)	-	1756388..1757482 (-)	1095	WP_044684682.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=704290 NKZ63_RS08810 WP_012775295.1 1751738..1752787(-) (sepM) [Streptococcus suis strain STC90]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=704290 NKZ63_RS08810 WP_012775295.1 1751738..1752787(-) (sepM) [Streptococcus suis strain STC90]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605