Detailed information NTG0067882

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ATE38_RS10615
• Genome accession: NZ_AP017377
• Coordinates: 2050587..2051630 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain OC8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2045587..2056630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ATE38_RS10585	-	2046005..2047261 (-)	1257	WP_001795438.1	aminopeptidase	-
ATE38_RS10590	-	2047264..2047464 (-)	201	WP_000180461.1	DUF1128 family protein	-
ATE38_RS10595	-	2047611..2048075 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ATE38_RS10600	-	2048082..2048357 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ATE38_RS10605	-	2048635..2049852 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ATE38_RS10610	vraR	2049968..2050597 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ATE38_RS10615	vraS	2050587..2051630 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ATE38_RS10620	liaF	2051627..2052328 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ATE38_RS10625	-	2052343..2052729 (-)	387	WP_001110179.1	hypothetical protein	-
ATE38_RS10630	map	2052946..2053704 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ATE38_RS10640	-	2054291..2055277 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
ATE38_RS10645	-	2055708..2056121 (-)	414	WP_001549145.1	hypothetical protein	-
ATE38_RS10650	-	2056150..2056260 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=67882 ATE38_RS10615 WP_001017131.1 2050587..2051630(-) (vraS) [Staphylococcus aureus strain OC8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=67882 ATE38_RS10615 WP_001017131.1 2050587..2051630(-) (vraS) [Staphylococcus aureus strain OC8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1