Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MUA85_RS04980 Genome accession   NZ_CP094799
Coordinates   1029393..1029962 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain IVB6159     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1024393..1034962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUA85_RS04960 (MUA85_04955) - 1025896..1027254 (+) 1359 WP_000021872.1 TrkH family potassium uptake protein -
  MUA85_RS04965 (MUA85_04960) - 1027393..1028904 (+) 1512 WP_000414178.1 bifunctional metallophosphatase/5'-nucleotidase -
  MUA85_RS04980 (MUA85_04975) comK/comK1 1029393..1029962 (-) 570 WP_000287265.1 competence protein ComK Regulator
  MUA85_RS04985 (MUA85_04980) - 1030172..1030390 (+) 219 WP_046597402.1 IDEAL domain-containing protein -
  MUA85_RS04990 (MUA85_04985) - 1030471..1031457 (-) 987 WP_000668812.1 lipoate--protein ligase -
  MUA85_RS04995 (MUA85_04990) - 1031656..1031832 (+) 177 WP_103150424.1 YkvS family protein -
  MUA85_RS05000 (MUA85_04995) - 1031847..1032449 (+) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  MUA85_RS05005 (MUA85_05000) - 1032766..1032828 (+) 63 WP_228764722.1 hypothetical protein -
  MUA85_RS05010 (MUA85_05005) - 1033367..1033465 (+) 99 Protein_980 hypothetical protein -
  MUA85_RS05015 (MUA85_05010) - 1033457..1033750 (+) 294 WP_000478235.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=672790 MUA85_RS04980 WP_000287265.1 1029393..1029962(-) (comK/comK1) [Staphylococcus aureus strain IVB6159]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=672790 MUA85_RS04980 WP_000287265.1 1029393..1029962(-) (comK/comK1) [Staphylococcus aureus strain IVB6159]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTATATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1