Detailed information NTG0671656

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA39_RS04960
• Genome accession: NZ_CP094739
• Coordinates: 1042150..1043193 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6219
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1037150..1048193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA39_RS04935 (MUA39_04920)	-	1037290..1038012 (+)	723	WP_262611974.1	type 1 glutamine amidotransferase	-
MUA39_RS04940 (MUA39_04925)	-	1039096..1040094 (-)	999	WP_262611975.1	aromatic acid exporter family protein	-
MUA39_RS04945 (MUA39_04930)	map	1040191..1040952 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
MUA39_RS04950 (MUA39_04935)	-	1041050..1041439 (+)	390	WP_262611976.1	hypothetical protein	-
MUA39_RS04955 (MUA39_04940)	liaF	1041452..1042153 (+)	702	WP_096597675.1	cell wall-active antibiotics response protein LiaF	-
MUA39_RS04960 (MUA39_04945)	vraS	1042150..1043193 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA39_RS04965 (MUA39_04950)	vraR	1043183..1043812 (+)	630	WP_262611977.1	response regulator transcription factor	Regulator
MUA39_RS04970 (MUA39_04955)	-	1044447..1045028 (-)	582	WP_262611978.1	carbonic anhydrase	-
MUA39_RS04975 (MUA39_04960)	-	1045061..1046407 (-)	1347	WP_262611979.1	YihY/virulence factor BrkB family protein	-
MUA39_RS04980 (MUA39_04965)	-	1046623..1046910 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA39_RS04985 (MUA39_04970)	-	1046918..1047376 (-)	459	WP_262611980.1	low molecular weight protein-tyrosine-phosphatase	-
MUA39_RS04990 (MUA39_04975)	-	1047510..1047713 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=671656 MUA39_RS04960 WP_019166463.1 1042150..1043193(+) (vraS) [Staphylococcus delphini strain IVB6219]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671656 MUA39_RS04960 WP_019166463.1 1042150..1043193(+) (vraS) [Staphylococcus delphini strain IVB6219]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTAAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTCGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACAGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836