Detailed information
Bioinformatically predicted
Overview
| Name | codY | Type | Regulator |
| Locus tag | L6176_RS18875 | Genome accession | NZ_CP091765 |
| Coordinates | 3644229..3645008 (-) | Length | 259 a.a. |
| NCBI ID | WP_000421288.1 | Uniprot ID | Q81WK7 |
| Organism | Bacillus anthracis strain PNO2D1 | ||
| Function | repression of comK (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 3609907..3683831 | 3644229..3645008 | within | 0 |
Gene organization within MGE regions
Location: 3609907..3683831
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6176_RS18725 (L6176_18725) | - | 3610251..3611921 (-) | 1671 | WP_000823085.1 | ribonuclease J | - |
| L6176_RS18730 (L6176_18730) | dapA | 3612687..3613565 (-) | 879 | WP_000564761.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| L6176_RS18735 (L6176_18735) | dapG | 3613577..3614809 (-) | 1233 | WP_000692470.1 | aspartate kinase | - |
| L6176_RS18740 (L6176_18740) | asd | 3614833..3615879 (-) | 1047 | WP_000414849.1 | aspartate-semialdehyde dehydrogenase | - |
| L6176_RS18745 (L6176_18745) | dpaB | 3616030..3616629 (-) | 600 | WP_001049484.1 | dipicolinate synthase subunit B | - |
| L6176_RS18750 (L6176_18750) | dpaA | 3616626..3617528 (-) | 903 | WP_000954726.1 | dipicolinic acid synthetase subunit A | - |
| L6176_RS18755 (L6176_18755) | - | 3617803..3618054 (-) | 252 | WP_001239752.1 | YlmC/YmxH family sporulation protein | - |
| L6176_RS18760 (L6176_18760) | - | 3618181..3619422 (-) | 1242 | WP_000592993.1 | pitrilysin family protein | - |
| L6176_RS18765 (L6176_18765) | - | 3619509..3620408 (-) | 900 | WP_000647529.1 | polysaccharide deacetylase family protein | - |
| L6176_RS18770 (L6176_18770) | pnp | 3620560..3622698 (-) | 2139 | WP_000076750.1 | polyribonucleotide nucleotidyltransferase | - |
| L6176_RS18775 (L6176_18775) | rpsO | 3622859..3623128 (-) | 270 | WP_001229392.1 | 30S ribosomal protein S15 | - |
| L6176_RS18780 (L6176_18780) | ribF | 3623229..3624200 (-) | 972 | WP_000766711.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| L6176_RS18785 (L6176_18785) | truB | 3624244..3625167 (-) | 924 | WP_000399357.1 | tRNA pseudouridine(55) synthase TruB | - |
| L6176_RS18790 (L6176_18790) | rbfA | 3625254..3625610 (-) | 357 | WP_000776446.1 | 30S ribosome-binding factor RbfA | - |
| L6176_RS18795 (L6176_18795) | - | 3625626..3625907 (-) | 282 | WP_000582364.1 | DUF503 domain-containing protein | - |
| L6176_RS18800 (L6176_18800) | infB | 3625904..3627964 (-) | 2061 | WP_000036339.1 | translation initiation factor IF-2 | - |
| L6176_RS18805 (L6176_18805) | - | 3627969..3628280 (-) | 312 | WP_001286523.1 | YlxQ family RNA-binding protein | - |
| L6176_RS18810 (L6176_18810) | rnpM | 3628281..3628553 (-) | 273 | WP_000071128.1 | RNase P modulator RnpM | - |
| L6176_RS18815 (L6176_18815) | nusA | 3628565..3629671 (-) | 1107 | WP_000102609.1 | transcription termination factor NusA | - |
| L6176_RS18820 (L6176_18820) | rimP | 3629689..3630159 (-) | 471 | WP_000359097.1 | ribosome maturation factor RimP | - |
| L6176_RS18825 (L6176_18825) | - | 3630492..3634793 (-) | 4302 | WP_000059985.1 | PolC-type DNA polymerase III | - |
| L6176_RS18830 (L6176_18830) | - | 3634918..3636618 (-) | 1701 | WP_000814312.1 | proline--tRNA ligase | - |
| L6176_RS18835 (L6176_18835) | rseP | 3636728..3637984 (-) | 1257 | WP_001090228.1 | RIP metalloprotease RseP | - |
| L6176_RS18840 (L6176_18840) | dxr | 3638001..3639143 (-) | 1143 | WP_000790359.1 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase | - |
| L6176_RS18845 (L6176_18845) | cdsA | 3639167..3639958 (-) | 792 | WP_000813581.1 | phosphatidate cytidylyltransferase | - |
| L6176_RS18850 (L6176_18850) | uppS | 3639976..3640752 (-) | 777 | WP_000971303.1 | isoprenyl transferase | - |
| L6176_RS18855 (L6176_18855) | frr | 3640838..3641395 (-) | 558 | WP_000531503.1 | ribosome recycling factor | - |
| L6176_RS18860 (L6176_18860) | pyrH | 3641398..3642120 (-) | 723 | WP_000042663.1 | UMP kinase | - |
| L6176_RS18865 (L6176_18865) | tsf | 3642187..3643074 (-) | 888 | WP_001018581.1 | translation elongation factor Ts | - |
| L6176_RS18870 (L6176_18870) | rpsB | 3643178..3643879 (-) | 702 | WP_000111483.1 | 30S ribosomal protein S2 | - |
| L6176_RS18875 (L6176_18875) | codY | 3644229..3645008 (-) | 780 | WP_000421288.1 | GTP-sensing pleiotropic transcriptional regulator CodY | Regulator |
| L6176_RS18880 (L6176_18880) | hslU | 3645086..3646477 (-) | 1392 | WP_000550088.1 | ATP-dependent protease ATPase subunit HslU | - |
| L6176_RS18885 (L6176_18885) | hslV | 3646500..3647042 (-) | 543 | WP_000526272.1 | ATP-dependent protease proteolytic subunit HslV | - |
| L6176_RS18890 (L6176_18890) | xerC | 3647085..3647984 (-) | 900 | WP_001101226.1 | tyrosine recombinase XerC | - |
| L6176_RS18895 (L6176_18895) | trmFO | 3648050..3649354 (-) | 1305 | WP_003161605.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| L6176_RS18900 (L6176_18900) | topA | 3649405..3651483 (-) | 2079 | WP_001286969.1 | type I DNA topoisomerase | - |
| L6176_RS18905 (L6176_18905) | dprA | 3651628..3652376 (-) | 749 | Protein_3700 | DNA-processing protein DprA | - |
| L6176_RS18910 (L6176_18910) | sucD | 3652584..3653486 (-) | 903 | WP_000115178.1 | succinate--CoA ligase subunit alpha | - |
| L6176_RS18915 (L6176_18915) | sucC | 3653507..3654667 (-) | 1161 | WP_001020786.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| L6176_RS18920 (L6176_18920) | rnhB | 3654861..3655634 (-) | 774 | WP_001174712.1 | ribonuclease HII | - |
| L6176_RS18925 (L6176_18925) | ylqF | 3655686..3656576 (-) | 891 | WP_000236707.1 | ribosome biogenesis GTPase YlqF | - |
| L6176_RS18930 (L6176_18930) | lepB | 3656597..3657148 (-) | 552 | WP_000711857.1 | signal peptidase I | - |
| L6176_RS18935 (L6176_18935) | rplS | 3657250..3657594 (-) | 345 | WP_001186516.1 | 50S ribosomal protein L19 | - |
| L6176_RS18940 (L6176_18940) | trmD | 3657741..3658475 (-) | 735 | WP_000686892.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| L6176_RS18945 (L6176_18945) | rimM | 3658475..3658990 (-) | 516 | WP_000170269.1 | ribosome maturation factor RimM | - |
| L6176_RS18950 (L6176_18950) | - | 3659111..3659338 (-) | 228 | WP_000737398.1 | KH domain-containing protein | - |
| L6176_RS18955 (L6176_18955) | rpsP | 3659353..3659625 (-) | 273 | WP_000268750.1 | 30S ribosomal protein S16 | - |
| L6176_RS18960 (L6176_18960) | ffh | 3659726..3661075 (-) | 1350 | WP_000863456.1 | signal recognition particle protein | - |
| L6176_RS18965 (L6176_18965) | - | 3661088..3661420 (-) | 333 | WP_000891062.1 | putative DNA-binding protein | - |
| L6176_RS18970 (L6176_18970) | ftsY | 3661554..3662543 (-) | 990 | WP_000007650.1 | signal recognition particle-docking protein FtsY | - |
| L6176_RS18975 (L6176_18975) | smc | 3662559..3666128 (-) | 3570 | WP_000478985.1 | chromosome segregation protein SMC | - |
| L6176_RS18980 (L6176_18980) | rncS | 3666275..3667012 (-) | 738 | WP_001146873.1 | ribonuclease III | - |
| L6176_RS18985 (L6176_18985) | acpP | 3667071..3667304 (-) | 234 | WP_000786062.1 | acyl carrier protein | - |
| L6176_RS18990 (L6176_18990) | fabG | 3667374..3668114 (-) | 741 | WP_000911782.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| L6176_RS18995 (L6176_18995) | fabD | 3668114..3669058 (-) | 945 | WP_000516958.1 | ACP S-malonyltransferase | - |
| L6176_RS19000 (L6176_19000) | plsX | 3669073..3670065 (-) | 993 | WP_000684111.1 | phosphate acyltransferase PlsX | - |
| L6176_RS19005 (L6176_19005) | fapR | 3670062..3670655 (-) | 594 | WP_000747352.1 | transcription factor FapR | - |
| L6176_RS19010 (L6176_19010) | recG | 3670744..3672792 (-) | 2049 | WP_001006884.1 | ATP-dependent DNA helicase RecG | - |
| L6176_RS19015 (L6176_19015) | - | 3673082..3674758 (-) | 1677 | WP_003158108.1 | DAK2 domain-containing protein | - |
| L6176_RS19020 (L6176_19020) | - | 3674781..3675143 (-) | 363 | WP_000021109.1 | Asp23/Gls24 family envelope stress response protein | - |
| L6176_RS19025 (L6176_19025) | rpmB | 3675522..3675710 (+) | 189 | WP_000124778.1 | 50S ribosomal protein L28 | - |
| L6176_RS19030 (L6176_19030) | spoVM | 3675783..3675863 (-) | 81 | WP_001213599.1 | stage V sporulation protein SpoVM | - |
| L6176_RS19035 (L6176_19035) | - | 3675930..3676610 (-) | 681 | WP_025388434.1 | thiamine diphosphokinase | - |
| L6176_RS19040 (L6176_19040) | rpe | 3676710..3677354 (-) | 645 | WP_000589966.1 | ribulose-phosphate 3-epimerase | - |
| L6176_RS19045 (L6176_19045) | rsgA | 3677357..3678238 (-) | 882 | WP_001113935.1 | ribosome small subunit-dependent GTPase A | - |
| L6176_RS19050 (L6176_19050) | prkC | 3678507..3680480 (-) | 1974 | WP_000904759.1 | serine/threonine protein kinase PrkC | - |
| L6176_RS19055 (L6176_19055) | - | 3680489..3681241 (-) | 753 | WP_000648699.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| L6176_RS19060 (L6176_19060) | rlmN | 3681246..3682334 (-) | 1089 | WP_000450543.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| L6176_RS19065 (L6176_19065) | rsmB | 3682339..3683673 (-) | 1335 | WP_001249680.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
Sequence
Protein
Download Length: 259 a.a. Molecular weight: 28774.05 Da Isoelectric Point: 4.7947
>NTDB_id=653450 L6176_RS18875 WP_000421288.1 3644229..3645008(-) (codY) [Bacillus anthracis strain PNO2D1]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN
Nucleotide
Download Length: 780 bp
>NTDB_id=653450 L6176_RS18875 WP_000421288.1 3644229..3645008(-) (codY) [Bacillus anthracis strain PNO2D1]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCGCGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCGCGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| codY | Bacillus subtilis subsp. subtilis str. 168 |
81.081 |
100 |
0.811 |
| codY | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.667 |
98.456 |
0.459 |