Detailed information NTG0645555

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: L1A11_RS09315
• Genome accession: NZ_CP090881
• Coordinates: 1798723..1799184 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BR1268
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1793723..1804184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A11_RS09285 (L1A11_09285)	-	1794027..1794851 (-)	825	WP_001809383.1	membrane protein insertase YidC	-
L1A11_RS09290 (L1A11_09290)	rnpA	1794826..1795197 (-)	372	WP_000739244.1	ribonuclease P protein component	-
L1A11_RS10465	-	1795214..1795345 (-)	132	WP_000768904.1	hypothetical protein	-
L1A11_RS09295 (L1A11_09295)	-	1795346..1796536 (-)	1191	WP_000167765.1	acetate kinase	-
L1A11_RS09300 (L1A11_09300)	comYH	1796587..1797540 (-)	954	WP_000345099.1	class I SAM-dependent methyltransferase	Machinery gene
L1A11_RS09305 (L1A11_09305)	-	1797601..1798195 (-)	595	Protein_1828	methyltransferase domain-containing protein	-
L1A11_RS09310 (L1A11_09310)	comGG/cglG	1798332..1798745 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
L1A11_RS09315 (L1A11_09315)	comGF/cglF	1798723..1799184 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
L1A11_RS09320 (L1A11_09320)	comGE/cglE	1799147..1799449 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
L1A11_RS09325 (L1A11_09325)	comGD/cglD	1799412..1799816 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
L1A11_RS09330 (L1A11_09330)	comGC/cglC	1799809..1800135 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
L1A11_RS09335 (L1A11_09335)	comGB/cglB	1800137..1801153 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
L1A11_RS09340 (L1A11_09340)	comGA/cglA/cilD	1801101..1802042 (-)	942	WP_000249552.1	competence type IV pilus ATPase ComGA	Machinery gene
L1A11_RS09345 (L1A11_09345)	-	1802118..1802483 (-)	366	WP_000286415.1	DUF1033 family protein	-
L1A11_RS09350 (L1A11_09350)	-	1802634..1803692 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=645555 L1A11_RS09315 WP_000250542.1 1798723..1799184(-) (comGF/cglF) [Streptococcus pneumoniae strain BR1268]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=645555 L1A11_RS09315 WP_000250542.1 1798723..1799184(-) (comGF/cglF) [Streptococcus pneumoniae strain BR1268]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909