Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   L1A02_RS10115 Genome accession   NZ_CP090873
Coordinates   2009236..2010210 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain SAUR_BFS16     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2004236..2015210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A02_RS10080 (L1A02_10080) rpmG 2004696..2004845 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  L1A02_RS10085 (L1A02_10085) - 2005054..2005593 (+) 540 WP_234863238.1 5-formyltetrahydrofolate cyclo-ligase -
  L1A02_RS10090 (L1A02_10090) - 2005605..2007068 (+) 1464 WP_001017867.1 rhomboid family protein -
  L1A02_RS10095 (L1A02_10095) - 2007049..2007252 (+) 204 WP_000087561.1 YqgQ family protein -
  L1A02_RS10100 (L1A02_10100) - 2007249..2008235 (+) 987 WP_000161314.1 ROK family glucokinase -
  L1A02_RS10105 (L1A02_10105) - 2008235..2008564 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  L1A02_RS10110 (L1A02_10110) - 2008561..2009184 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  L1A02_RS10115 (L1A02_10115) comGA 2009236..2010210 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A02_RS10120 (L1A02_10120) comGB 2010182..2011252 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A02_RS10125 (L1A02_10125) comGC 2011266..2011577 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  L1A02_RS10130 (L1A02_10130) comGD 2011555..2012001 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A02_RS10135 (L1A02_10135) comGE 2011988..2012287 (+) 300 WP_000844410.1 hypothetical protein Machinery gene
  L1A02_RS10140 (L1A02_10140) comGF 2012205..2012702 (+) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A02_RS10145 (L1A02_10145) - 2012799..2012945 (+) 147 WP_001792109.1 hypothetical protein -
  L1A02_RS10150 (L1A02_10150) - 2012935..2013459 (+) 525 WP_001015120.1 shikimate kinase -
  L1A02_RS10155 (L1A02_10155) gcvT 2013618..2014709 (+) 1092 WP_103153623.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=645356 L1A02_RS10115 WP_000697220.1 2009236..2010210(+) (comGA) [Staphylococcus aureus strain SAUR_BFS16]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=645356 L1A02_RS10115 WP_000697220.1 2009236..2010210(+) (comGA) [Staphylococcus aureus strain SAUR_BFS16]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGCGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1