Detailed information NTG0623806

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: LLZ98_RS05870
• Genome accession: NZ_CP086215
• Coordinates: 1141883..1142869 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain Patient 14 Isolate 02
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1136883..1147869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLZ98_RS05845 (LLZ98_05850)	-	1137143..1137490 (-)	348	WP_001242103.1	hypothetical protein	-
LLZ98_RS05850 (LLZ98_05855)	-	1137676..1138269 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
LLZ98_RS05855 (LLZ98_05860)	-	1138373..1138738 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
LLZ98_RS05860 (LLZ98_05865)	yjbH	1138761..1139567 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
LLZ98_RS05865 (LLZ98_05870)	pepF	1140027..1141835 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
LLZ98_RS05870 (LLZ98_05875)	coiA	1141883..1142869 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
LLZ98_RS05875 (LLZ98_05880)	mecA	1142990..1143709 (-)	720	WP_001217728.1	adaptor protein MecA	-
LLZ98_RS05880 (LLZ98_05885)	spxA	1144080..1144475 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
LLZ98_RS05885 (LLZ98_05890)	trpS	1144769..1145758 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
LLZ98_RS05890 (LLZ98_05895)	opp4C	1145800..1146681 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
LLZ98_RS05895 (LLZ98_05900)	opp4B	1146693..1147655 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=623806 LLZ98_RS05870 WP_000959282.1 1141883..1142869(-) (coiA) [Staphylococcus aureus strain Patient 14 Isolate 02]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=623806 LLZ98_RS05870 WP_000959282.1 1141883..1142869(-) (coiA) [Staphylococcus aureus strain Patient 14 Isolate 02]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976