Detailed information NTG0061508

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SII_RS00680
• Genome accession: NC_022237
• Coordinates: 141210..143639 (+)
• Length: 809 a.a.
• NCBI ID: WP_020998211.1
• Uniprot ID: -
• Organism: Streptococcus intermedius C270
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 136210..148639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SII_RS00650 (SII_0132)	-	136724..137509 (+)	786	WP_020998210.1	hypothetical protein	-
SII_RS00660 (SII_0134)	rpsB	138151..138933 (+)	783	WP_003074779.1	30S ribosomal protein S2	-
SII_RS00665 (SII_0135)	tsf	139016..140059 (+)	1044	WP_003074777.1	translation elongation factor Ts	-
SII_RS00670 (SII_0136)	-	140136..140486 (-)	351	WP_009567828.1	hypothetical protein	-
SII_RS00675 (SII_0137)	-	140745..141206 (+)	462	WP_003077510.1	CtsR family transcriptional regulator	-
SII_RS00680 (SII_0138)	clpC	141210..143639 (+)	2430	WP_020998211.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SII_RS00685 (SII_0139)	-	143686..144126 (+)	441	WP_003074768.1	GNAT family N-acetyltransferase	-
SII_RS00690 (SII_0140)	dusB	144197..145168 (-)	972	WP_003074765.1	tRNA dihydrouridine synthase DusB	-
SII_RS00695 (SII_0141)	hslO	145155..146027 (-)	873	WP_041823105.1	Hsp33 family molecular chaperone HslO	-
SII_RS00700 (SII_0142)	-	146236..147507 (-)	1272	WP_020998213.1	toxic anion resistance protein	-
SII_RS00705 (SII_0143)	-	147526..148344 (-)	819	WP_020998214.1	hypothetical protein	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 90081.32 Da
• Isoelectric Point: 6.0573

>NTDB_id=61508 SII_RS00680 WP_020998211.1 141210..143639(+) (clpC) [Streptococcus intermedius C270]
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPF
SYRMKVLFLTAEQIAGAVHANNLGTEHILLAMLFDQGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKSAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRILQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALAKGTLRTIGATTQEEYQKYIEKDAALSRRFAKVTIEEPTVADSIAILQGLKKSYEDHHKVVITDSAIEM
AVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVDTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFLFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVK
AGKLKFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=61508 SII_RS00680 WP_020998211.1 141210..143639(+) (clpC) [Streptococcus intermedius C270]
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAAA
TTGATGATTTTGAAAAGGCAGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGACTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGCTATTTTTGACTGCTGAACAAATTGCAGGGGCGGTTCATGCTAATAATCTTGGGACAGAGCA
TATATTGCTAGCTATGTTATTTGACCAAGGAAGCTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGTGTTTTGCGCATGACAGATCTGCGGAAAAATTTAGAGCATAAGGCCAGCTGGAATAAAGAGGATTTAAAGGCT
ATTCGTCACCTAAATAAAAGTGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATACTTCAGATTTTAAGTCGTAAGACAAAAAACAATCCGGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCTCTGGGTTTGGCGCAACGTGTGGCAGATGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAAGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGGCATGTTATTCTCTTCATTGATGAGCTTCATACCATTATGGGGTCTGGCAGCGGGATTGACTCGACA
TTAGATGCAGCAAATATTCTCAAGCCGGCTTTGGCTAAAGGAACGCTCAGAACGATCGGTGCCACAACACAAGAAGAGTA
CCAAAAATATATCGAAAAAGATGCAGCTCTTTCACGAAGATTTGCCAAGGTTACTATTGAAGAACCAACGGTAGCTGACA
GCATTGCTATTTTACAGGGACTCAAGAAAAGTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCAATTGAGATG
GCTGTTAAGTATGCGCATCGTTACCTGACTAGTAAACATCTACCTGACTCAGCGATTGACTTGCTAGACGAAGCTGCTGC
AAGGGTACAAAATAAAAGCCCGCAAAATCACGTAAAAGCAGAATTGAGTGCAGCAGATGAGGCTTTAATGGCAGGCGATT
GGAACAAAGTTGATACGTTGTTGGAGAAAGAGAGTCAGCCAATTGTTTATAAATTAAGAGTGAAAGACGAGGATGTTTTA
GCAACACTCAGCAGTTTATCAGGTATTCCTGTGCAAAAGTTGACACAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAGTTACACAAACGAGTTATCGGGCAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCCGGTA
TCCGCACTAGCAAGCGCCCAATTGGCTCCTTTCTGTTCTTAGGGCCAACTGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCGTTAATTCGTTTTGATATGTCCGAATACATGGAGAAATTTGCTGCTAG
TCGTCTCAATGGAGCACCTCCAGGCTATGTTGGTTATGAAGAAGGGGGAGAATTAACTGAAAAGGTGCGTAATCGTCCTT
ACTCTGTGCTCCTCTTTGATGAGGTAGAAAAAGCACATCCTGATATTTTCAATGTGCTGCTCCAAGTCTTAGATGACGGG
GTTCTGACGGATAGCAAGGGCCGTAAGGTAGATTTTTCCAATACTATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTACGGGACGATAAGACGGTTGGGTTCGGAGCAAGAGATGTTCGCTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGACGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
ACCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGCCCATTGCGTCGAATTCTACAAA
CTCGAGTGGAAGACCATTTATCAGAATTACTTTTAGCAGGTGAGCTAAAAACGGGACAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• AAA lid domain (AAA_lid_9) (371-446)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	76.819	100	0.77
clpC	Streptococcus pneumoniae Rx1	76.819	100	0.77
clpC	Streptococcus pneumoniae D39	76.819	100	0.77
clpC	Streptococcus mutans UA159	66.38	100	0.669
clpC	Streptococcus thermophilus LMG 18311	64.988	100	0.654
clpC	Streptococcus thermophilus LMD-9	64.865	100	0.653
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.399	100	0.508
clpC	Bacillus subtilis subsp. subtilis str. 168	45.885	99.135	0.455