Detailed information NTG0585181

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KU530_RS09855
• Genome accession: NZ_CP077921
• Coordinates: 2026337..2027224 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 276
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021337..2032224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU530_RS09825 (KU530_09790)	-	2022069..2022830 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
KU530_RS09830 (KU530_09795)	-	2023075..2023530 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KU530_RS13475	-	2023652..2023753 (+)	102	WP_000731972.1	SE2200 family small protein	-
KU530_RS09840 (KU530_09805)	-	2023813..2025237 (-)	1425	WP_000953748.1	alkaline phosphatase	-
KU530_RS09845 (KU530_09810)	-	2025435..2025635 (+)	201	WP_000604727.1	hypothetical protein	-
KU530_RS09850 (KU530_09815)	braR	2025661..2026326 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KU530_RS09855 (KU530_09820)	braS	2026337..2027224 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KU530_RS09860 (KU530_09825)	-	2027332..2028087 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
KU530_RS09865 (KU530_09830)	-	2028084..2030084 (+)	2001	WP_000776740.1	ABC transporter permease	-
KU530_RS09870 (KU530_09835)	-	2030743..2030856 (+)	114	Protein_1910	hypothetical protein	-
KU530_RS09875 (KU530_09840)	-	2031238..2031498 (+)	261	WP_001791974.1	hypothetical protein	-
KU530_RS09880 (KU530_09845)	-	2031508..2032005 (+)	498	WP_001065268.1	glutathione peroxidase	-
KU530_RS09885 (KU530_09850)	-	2032113..2032205 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=585181 KU530_RS09855 WP_000143417.1 2026337..2027224(+) (braS) [Staphylococcus aureus strain 276]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=585181 KU530_RS09855 WP_000143417.1 2026337..2027224(+) (braS) [Staphylococcus aureus strain 276]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99