Detailed information NTG0575414

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: KO461_RS01235
• Genome accession: NZ_CP076449
• Coordinates: 225843..226961 (-)
• Length: 372 a.a.
• NCBI ID: WP_005540807.1
• Uniprot ID: A0A142FZH0
• Organism: Aggregatibacter actinomycetemcomitans strain CU1000N
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 220843..231961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KO461_RS01220 (KO461_01210)	rlmB	221961..222698 (+)	738	WP_005564538.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
KO461_RS01225 (KO461_01215)	glpT	223031..224473 (+)	1443	WP_005540804.1	glycerol-3-phosphate transporter	-
KO461_RS01230 (KO461_01220)	glpQ	224705..225787 (+)	1083	WP_205764796.1	glycerophosphodiester phosphodiesterase	-
KO461_RS01235 (KO461_01225)	dprA	225843..226961 (-)	1119	WP_005540807.1	DNA-processing protein DprA	Machinery gene
KO461_RS01240 (KO461_01230)	rplI	227179..227628 (-)	450	WP_005564536.1	50S ribosomal protein L9	-
KO461_RS01245 (KO461_01235)	rpsR	227644..227874 (-)	231	WP_005541294.1	30S ribosomal protein S18	-
KO461_RS01250 (KO461_01240)	priB	227887..228213 (-)	327	WP_005544874.1	primosomal replication protein N	-
KO461_RS01255 (KO461_01245)	rpsF	228200..228577 (-)	378	WP_005541284.1	30S ribosomal protein S6	-
KO461_RS01260 (KO461_01250)	lexA	228729..229352 (-)	624	WP_005564535.1	transcriptional repressor LexA	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41696.85 Da
• Isoelectric Point: 6.4278

>NTDB_id=575414 KO461_RS01235 WP_005540807.1 225843..226961(-) (dprA) [Aggregatibacter actinomycetemcomitans strain CU1000N]
MNKHLALLLRLLQIPKLGPTTIHKILAQVNLSELQYYDAAAFTQMGWNAQQIQAWFHPEQRYIEPALLWGEKEGNHILDY
FHPDYPELLKQIESAPPVLFVKGATSALSQQQIAIVGSRQCSSYGEYWAKYFATELTTNGFIITSGLALGIDGFCHQAAV
DLKQPTIAVLGSGLEEVYPAKHRKLAQNIIEHDGALVSEFFPLQPPIAENFPRRNRIISGLSLATLIIEATERSGSLITA
RYALEQNREIFALPGNIQSQFSQGCHKLIKQGAMLVENVEDILENLAPQMTWKKRPQNRPHFSAIRKTTSTSLPPPVTPS
HPELYNIIGYNPISADDLSTTLNLSIDQILIQLLELELQDLIISENGLYRRV

Nucleotide

• Length: 1119 bp

>NTDB_id=575414 KO461_RS01235 WP_005540807.1 225843..226961(-) (dprA) [Aggregatibacter actinomycetemcomitans strain CU1000N]
ATGAACAAACATTTAGCACTTTTACTGCGCCTATTACAAATCCCCAAATTAGGCCCCACCACAATCCATAAAATCCTTGC
TCAAGTGAATTTATCCGAATTGCAATATTACGACGCGGCTGCATTTACGCAAATGGGCTGGAACGCACAACAGATTCAAG
CATGGTTTCATCCGGAGCAGCGCTATATTGAACCGGCACTTTTATGGGGAGAGAAAGAAGGAAATCATATTCTTGATTAT
TTTCACCCTGATTATCCCGAATTATTAAAACAAATCGAAAGCGCACCGCCGGTATTGTTCGTCAAAGGCGCGACAAGTGC
GCTATCACAGCAACAAATCGCTATTGTCGGTAGCCGCCAATGTTCAAGTTATGGTGAATATTGGGCGAAATATTTTGCCA
CGGAATTAACCACCAACGGTTTCATCATTACCAGCGGGTTGGCGTTAGGCATTGATGGTTTCTGCCATCAGGCTGCGGTC
GATTTAAAACAACCGACCATCGCCGTTTTAGGCAGCGGACTGGAAGAAGTGTATCCCGCCAAACATCGCAAATTAGCGCA
GAATATTATTGAACATGATGGTGCGTTGGTTTCTGAATTTTTCCCGCTACAACCACCGATTGCCGAAAATTTTCCCCGCC
GCAATCGCATTATCAGCGGGTTATCATTAGCGACCTTAATTATTGAAGCCACCGAACGCAGCGGATCATTAATTACGGCA
CGCTATGCGTTAGAACAAAACAGAGAAATTTTTGCACTACCGGGCAATATTCAAAGCCAGTTCAGCCAAGGCTGCCATAA
GCTTATTAAACAAGGCGCAATGCTGGTCGAAAACGTGGAAGATATTTTAGAAAATCTTGCGCCACAAATGACATGGAAAA
AACGCCCGCAAAATCGACCGCACTTTTCCGCTATAAGGAAAACAACGTCCACCTCATTACCGCCTCCCGTCACGCCATCC
CACCCCGAGCTATACAATATTATTGGTTATAACCCGATAAGCGCAGATGATTTATCTACAACACTTAATCTGTCTATTGA
TCAAATTCTCATTCAATTGCTGGAGCTGGAATTACAGGATTTAATTATCAGTGAAAACGGATTATATCGGCGGGTTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-365)

3D structure

• AlphaFold DB: A0A142FZH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	63.564	100	0.642
dprA	Glaesserella parasuis strain SC1401	55.966	94.624	0.53
dprA	Vibrio campbellii strain DS40M4	44.293	98.925	0.438
dprA	Vibrio cholerae strain A1552	43.316	100	0.435
dprA	Legionella pneumophila strain ERS1305867	40.541	99.462	0.403