Detailed information NTG0057035

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SAI7S6_RS04630
• Genome accession: NC_020537
• Coordinates: 950822..951808 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 945822..956808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI7S6_RS04605 (SAI7S6_1007000)	opp4B	946036..946998 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
SAI7S6_RS04610 (SAI7S6_1007010)	opp4C	947010..947891 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
SAI7S6_RS04615 (SAI7S6_1007020)	trpS	947933..948922 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
SAI7S6_RS04620	spxA	949216..949611 (+)	396	WP_041174200.1	transcriptional regulator SpxA	-
SAI7S6_RS04625 (SAI7S6_1007030)	mecA	949982..950701 (+)	720	WP_001217728.1	adaptor protein MecA	-
SAI7S6_RS04630 (SAI7S6_1007040)	coiA	950822..951808 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
SAI7S6_RS04635 (SAI7S6_1007050)	pepF	951856..953664 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
SAI7S6_RS04640 (SAI7S6_1007060)	yjbH	954124..954930 (-)	807	WP_015445788.1	protease adaptor protein YjbH	-
SAI7S6_RS04645	-	954953..955318 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
SAI7S6_RS04650 (SAI7S6_1007070)	-	955422..956015 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
SAI7S6_RS04655	-	956201..956548 (+)	348	WP_001242109.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=57035 SAI7S6_RS04630 WP_000959282.1 950822..951808(+) (coiA) [Staphylococcus aureus subsp. aureus ST228]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=57035 SAI7S6_RS04630 WP_000959282.1 950822..951808(+) (coiA) [Staphylococcus aureus subsp. aureus ST228]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976