Detailed information NTG0553338

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7T63_RS05540
• Genome accession: NZ_CP072442
• Coordinates: 1051955..1052662 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24726
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1046955..1057662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T63_RS05515 (J7T63_05515)	yidA	1047306..1048115 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7T63_RS05520 (J7T63_05520)	-	1048117..1049331 (+)	1215	WP_002953123.1	aminoacyltransferase	-
J7T63_RS05525 (J7T63_05525)	-	1049383..1049744 (-)	362	Protein_1033	YbaN family protein	-
J7T63_RS05530 (J7T63_05530)	vicX	1049804..1050616 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7T63_RS05535 (J7T63_05535)	vicK	1050622..1051962 (-)	1341	WP_372429118.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7T63_RS05540 (J7T63_05540)	vicR	1051955..1052662 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7T63_RS05545 (J7T63_05545)	-	1053198..1053965 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7T63_RS05550 (J7T63_05550)	-	1053977..1054810 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7T63_RS05555 (J7T63_05555)	-	1054828..1055526 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7T63_RS05560 (J7T63_05560)	-	1055538..1056188 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7T63_RS05565 (J7T63_05565)	endA	1056260..1057141 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7T63_RS05570 (J7T63_05570)	-	1057203..1057391 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=553338 J7T63_RS05540 WP_011681206.1 1051955..1052662(-) (vicR) [Streptococcus thermophilus strain S24726]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=553338 J7T63_RS05540 WP_011681206.1 1051955..1052662(-) (vicR) [Streptococcus thermophilus strain S24726]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387