Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   J7T60_RS08665 Genome accession   NZ_CP072436
Coordinates   1649404..1650345 (-) Length   313 a.a.
NCBI ID   WP_180478282.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24735     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1644404..1655345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T60_RS08625 (J7T60_08520) - 1644480..1645673 (-) 1194 WP_014608740.1 acetate kinase -
  J7T60_RS08630 (J7T60_08525) comYH 1645729..1646685 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  J7T60_RS08635 (J7T60_08530) comGG 1646730..1647047 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  J7T60_RS08640 (J7T60_08535) comYF 1647025..1647462 (-) 438 WP_372433445.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7T60_RS08645 (J7T60_08540) comGE 1647446..1647739 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  J7T60_RS08650 (J7T60_08545) comYD 1647711..1648139 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7T60_RS08655 (J7T60_08550) comYC 1648099..1648425 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7T60_RS08660 (J7T60_08555) comYB 1648422..1649522 (-) 1101 WP_372433576.1 competence type IV pilus assembly protein ComGB Machinery gene
  J7T60_RS08665 (J7T60_08560) comYA 1649404..1650345 (-) 942 WP_180478282.1 competence type IV pilus ATPase ComGA Machinery gene
  J7T60_RS08670 (J7T60_08565) - 1650426..1650788 (-) 363 WP_372433446.1 DUF1033 family protein -
  J7T60_RS08675 (J7T60_08570) rpoC 1650947..1654585 (-) 3639 WP_011681690.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35439.59 Da        Isoelectric Point: 6.3927

>NTDB_id=553013 J7T60_RS08665 WP_180478282.1 1649404..1650345(-) (comYA) [Streptococcus thermophilus strain S24735]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQTIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=553013 J7T60_RS08665 WP_180478282.1 1649404..1650345(-) (comYA) [Streptococcus thermophilus strain S24735]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCTATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGACGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTCTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

63.578

100

0.636
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.538

99.681

0.613
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.816

97.125

0.377