Detailed information NTG0552906

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7U23_RS01490
• Genome accession: NZ_CP072435
• Coordinates: 268380..269279 (+)
• Length: 299 a.a.
• NCBI ID: WP_372589944.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24736
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 263380..274279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS01470 (J7U23_01460)	trkA	264517..265866 (-)	1350	WP_084829332.1	Trk system potassium transporter TrkA	-
J7U23_RS01475 (J7U23_01465)	-	266125..266664 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7U23_RS01480 (J7U23_01470)	-	266975..267532 (+)	558	WP_024704183.1	ECF transporter S component	-
J7U23_RS01485 (J7U23_01475)	-	267535..268185 (+)	651	WP_084829333.1	phosphatase PAP2 family protein	-
J7U23_RS01490 (J7U23_01480)	comR	268380..269279 (+)	900	WP_372589944.1	helix-turn-helix domain-containing protein	Regulator
J7U23_RS01495	-	269517..270695 (+)	1179	Protein_241	ABC transporter transmembrane domain-containing protein	-
J7U23_RS01500	comA	270717..271550 (+)	834	WP_269149495.1	ATP-binding cassette domain-containing protein	Regulator
J7U23_RS01505 (J7U23_01490)	-	271658..271975 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
J7U23_RS01510	-	272191..272538 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
J7U23_RS01515	-	272463..273083 (-)	621	WP_232085704.1	DUF4153 domain-containing protein	-
J7U23_RS01520 (J7U23_01500)	-	273764..274279 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35331.82 Da
• Isoelectric Point: 5.1073

>NTDB_id=552906 J7U23_RS01490 WP_372589944.1 268380..269279(+) (comR) [Streptococcus thermophilus strain S24736]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALVVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=552906 J7U23_RS01490 WP_372589944.1 268380..269279(+) (comR) [Streptococcus thermophilus strain S24736]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGATTTCTTAACAGTTGTGGATAAAGCCTTAGTTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	99.331	100	0.993
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418