Detailed information NTG0552787

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7U07_RS01440
• Genome accession: NZ_CP072433
• Coordinates: 258879..259778 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24743
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 253879..264778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U07_RS01420 (J7U07_01400)	trkA	255015..256364 (-)	1350	WP_372588697.1	Trk system potassium transporter TrkA	-
J7U07_RS01425 (J7U07_01405)	-	256653..257162 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7U07_RS01430 (J7U07_01410)	-	257474..258031 (+)	558	WP_002949523.1	ECF transporter S component	-
J7U07_RS01435 (J7U07_01415)	-	258034..258684 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
J7U07_RS01440 (J7U07_01420)	comR	258879..259778 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7U07_RS01445	-	260015..260446 (+)	432	Protein_231	cysteine peptidase family C39 domain-containing protein	-
J7U07_RS01450	-	260476..261192 (+)	717	Protein_232	ABC transporter transmembrane domain-containing protein	-
J7U07_RS01455	comA	261214..262047 (+)	834	WP_269149495.1	ATP-binding cassette domain-containing protein	Regulator
J7U07_RS01460 (J7U07_01430)	-	262155..262472 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
J7U07_RS01465	-	262688..263035 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
J7U07_RS01470	-	262960..263580 (-)	621	WP_232085704.1	DUF4153 domain-containing protein	-
J7U07_RS01475 (J7U07_01440)	-	264261..264776 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=552787 J7U07_RS01440 WP_014607953.1 258879..259778(+) (comR) [Streptococcus thermophilus strain S24743]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=552787 J7U07_RS01440 WP_014607953.1 258879..259778(+) (comR) [Streptococcus thermophilus strain S24743]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418