Detailed information NTG0543154

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: JZI48_RS02020
• Genome accession: NZ_CP071145
• Coordinates: 434951..435988 (-)
• Length: 345 a.a.
• NCBI ID: WP_012679161.1
• Uniprot ID: C0MBZ2
• Organism: Streptococcus equi subsp. equi strain 470_007
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 429951..440988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI48_RS02000 (JZI48_02000)	-	430183..430659 (+)	477	WP_250880203.1	hypothetical protein	-
JZI48_RS02005 (JZI48_02005)	-	430679..432021 (+)	1343	WP_173292356.1	IS3 family transposase	-
JZI48_RS10920	-	432053..432256 (+)	204	Protein_403	peptidase	-
JZI48_RS02010 (JZI48_02010)	rlmN	432689..433771 (-)	1083	WP_012679163.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
JZI48_RS02015 (JZI48_02015)	-	433775..434389 (-)	615	WP_012679162.1	YutD family protein	-
JZI48_RS02020 (JZI48_02020)	sepM	434951..435988 (-)	1038	WP_012679161.1	SepM family pheromone-processing serine protease	Regulator
JZI48_RS02025 (JZI48_02025)	coaD	435966..436466 (-)	501	WP_012679160.1	pantetheine-phosphate adenylyltransferase	-
JZI48_RS02030 (JZI48_02030)	rsmD	436456..436995 (-)	540	WP_012679159.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
JZI48_RS02035 (JZI48_02035)	asnA	437167..438159 (-)	993	WP_012679158.1	aspartate--ammonia ligase	-
JZI48_RS02040 (JZI48_02040)	arcC	438379..439329 (-)	951	WP_012679157.1	carbamate kinase	-
JZI48_RS02045 (JZI48_02045)	-	439347..440678 (-)	1332	WP_012679156.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37438.09 Da
• Isoelectric Point: 9.4223

>NTDB_id=543154 JZI48_RS02020 WP_012679161.1 434951..435988(-) (sepM) [Streptococcus equi subsp. equi strain 470_007]
MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=543154 JZI48_RS02020 WP_012679161.1 434951..435988(-) (sepM) [Streptococcus equi subsp. equi strain 470_007]
ATGAAAACAATAAAAAAAATTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACTGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGCATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: C0MBZ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.855	100	0.699