Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I2439_RS07255 Genome accession   NZ_CP065191
Coordinates   1526487..1527197 (-) Length   236 a.a.
NCBI ID   WP_012677635.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1521487..1532197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS07240 (HIEAAJJG_01468) - 1522395..1524065 (-) 1671 WP_255313971.1 restriction endonuclease FokI C-terminal domain-containing protein -
  I2439_RS07245 (HIEAAJJG_01470) vicX 1524329..1525138 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2439_RS07250 (HIEAAJJG_01471) vicK 1525142..1526494 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2439_RS07255 (HIEAAJJG_01472) vicR 1526487..1527197 (-) 711 WP_012677635.1 response regulator YycF Regulator
  I2439_RS07260 (HIEAAJJG_01473) - 1527406..1528422 (-) 1017 WP_043039171.1 DUF3114 domain-containing protein -
  I2439_RS07265 (HIEAAJJG_01474) - 1528468..1529730 (-) 1263 WP_043039172.1 AMP-binding protein -
  I2439_RS07270 (HIEAAJJG_01475) - 1529720..1530835 (-) 1116 WP_043039173.1 acetyl-CoA C-acyltransferase -
  I2439_RS07275 (HIEAAJJG_01476) - 1530832..1531371 (-) 540 WP_043039174.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26967.81 Da        Isoelectric Point: 4.9038

>NTDB_id=507834 I2439_RS07255 WP_012677635.1 1526487..1527197(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=507834 I2439_RS07255 WP_012677635.1 1526487..1527197(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAATTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCTGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACTATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
TTGACCCATCGTGAGTTTGAATTGCTGCATCACCTGGCAAACCATATTGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTATGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTGTCCGTCGCCTGCGTGAAAAAATAGAGG
ACACACCGAGTCGTCCGGAGTACATCTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.407

100

0.894
  micA Streptococcus pneumoniae Cp1015

78.541

98.729

0.775
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  covR Streptococcus salivarius strain HSISS4

43.966

98.305

0.432
  scnR Streptococcus mutans UA159

37.607

99.153

0.373