Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I2437_RS03145 Genome accession   NZ_CP065061
Coordinates   625908..626630 (+) Length   240 a.a.
NCBI ID   WP_012677660.1    Uniprot ID   A0AAW3GL08
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ33     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 620908..631630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2437_RS03125 (IEMOCGPF_00620) - 622216..623637 (+) 1422 WP_206157955.1 glycoside hydrolase family 1 protein -
  I2437_RS03130 (IEMOCGPF_00621) - 623823..624638 (-) 816 WP_043052244.1 TIGR03943 family protein -
  I2437_RS03135 (IEMOCGPF_00622) - 624638..625540 (-) 903 WP_021320980.1 permease -
  I2437_RS03140 (IEMOCGPF_00623) - 625581..625736 (-) 156 WP_012515968.1 SPJ_0845 family protein -
  I2437_RS03145 (IEMOCGPF_00624) vicR 625908..626630 (+) 723 WP_012677660.1 response regulator transcription factor Regulator
  I2437_RS03150 (IEMOCGPF_00625) - 626614..627939 (+) 1326 WP_206157956.1 ATP-binding protein -
  I2437_RS03155 (IEMOCGPF_00626) - 628098..628970 (+) 873 WP_021320979.1 substrate-binding domain-containing protein -
  I2437_RS03160 (IEMOCGPF_00627) pstC 629040..629903 (+) 864 WP_012677663.1 phosphate ABC transporter permease subunit PstC -
  I2437_RS03165 (IEMOCGPF_00628) pstA 629896..630711 (+) 816 WP_021320978.1 phosphate ABC transporter permease PstA -
  I2437_RS03170 (IEMOCGPF_00629) pstB 630713..631465 (+) 753 WP_012677665.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28111.54 Da        Isoelectric Point: 6.1653

>NTDB_id=506601 I2437_RS03145 WP_012677660.1 625908..626630(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAEREPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMV
SAKSDEFDKVLALELGADDYVTKPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQYIQTIRGYGYKFKELKNDRTS

Nucleotide


Download         Length: 723 bp        

>NTDB_id=506601 I2437_RS03145 WP_012677660.1 625908..626630(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGACAAAACGAGTATTATTAGTAGATGATGAGGAGCCTATCTTAAGGCTACTGGATTATCACTTGGCCAAGGAGGGCTT
TGTGACAGAGATGGTAACAGATGGCCGTACTGCCTTGGCATTAGCTGAAAGAGAACCTTATGATTTTATTGTGTTAGATA
TTATGCTGCCGCAATTAGACGGTATCGAGGTCTGCAAAAGGCTTCGTGCTAAGGGAAGCAAAACCCCAATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGACAAGGTTTTGGCTTTGGAACTGGGGGCAGATGATTATGTGACCAAGCCCTTTAGTCC
TAGAGAATTATTAGCGCGTGTCAAGGCTATTTTAAGGCGCACTGAAGCAGAGATTTCTGGTGATGGTGAGGAGCGTCGTG
AGCCTTTTTATACGATGAGTCAATTGCGTCTGTACCCAGAGCGACATGAGGTCTATAAGGACAAGGAGCTATTGCCGTTA
ACCCCAAAGGAATATGAGCTACTGCTCTATCTCATGAAGCACCCTAATATGACCTTGACGCGTGAGCGGCTATTAGAGCG
TATCTGGGGTTATGACTTTGGCCAAGAAACACGTCTGGTAGACGTTCATATTGGCAAGCTCAGAGAAAAAATTGAGGACA
ATCCTAAGGCGCCTCAGTATATTCAAACCATTCGCGGCTATGGATACAAATTTAAGGAGCTAAAGAATGATAGGACATCT
TAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(158-231)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

52.155

96.667

0.504
  micA Streptococcus pneumoniae Cp1015

50

95.833

0.479
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.017

97.5

0.429
  covR Streptococcus salivarius strain HSISS4

40.773

97.083

0.396