Detailed information NTG0502376

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI53_RS04305
• Genome accession: NZ_CP064494
• Coordinates: 929545..930591 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG380
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 924545..935591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI53_RS04280 (HWI53_04255)	isaB	925686..926222 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI53_RS04285 (HWI53_04260)	-	926373..927359 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI53_RS04290 (HWI53_04265)	map	927533..928288 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI53_RS04295 (HWI53_04270)	-	928446..928832 (+)	387	WP_001830382.1	hypothetical protein	-
HWI53_RS04300 (HWI53_04275)	liaF	928847..929548 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI53_RS04305 (HWI53_04280)	vraS	929545..930591 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI53_RS04310 (HWI53_04285)	vraR	930581..931210 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI53_RS04315 (HWI53_04290)	-	931267..932445 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI53_RS04320 (HWI53_04295)	-	932852..933136 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI53_RS04325 (HWI53_04300)	-	933144..933608 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI53_RS04330 (HWI53_04305)	-	933749..933964 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI53_RS04335 (HWI53_04310)	-	933966..935207 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=502376 HWI53_RS04305 WP_002486322.1 929545..930591(+) (vraS) [Staphylococcus epidermidis strain UMCG380]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=502376 HWI53_RS04305 WP_002486322.1 929545..930591(+) (vraS) [Staphylococcus epidermidis strain UMCG380]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917