Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   IUJ45_RS04405 Genome accession   NZ_CP064367
Coordinates   845425..847734 (+) Length   769 a.a.
NCBI ID   WP_002261352.1    Uniprot ID   -
Organism   Neisseria meningitidis strain PartJ-Nmeningitidis-RM8376     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 840425..852734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ45_RS04385 (IUJ45_04445) - 842478..843593 (+) 1116 WP_002214517.1 type IV pilus biogenesis protein PilM -
  IUJ45_RS04390 (IUJ45_04450) pilN 843596..844195 (+) 600 WP_002214520.1 PilN domain-containing protein Machinery gene
  IUJ45_RS04395 (IUJ45_04455) pilO 844196..844843 (+) 648 WP_002214521.1 type 4a pilus biogenesis protein PilO -
  IUJ45_RS04400 (IUJ45_04460) pilP 844861..845406 (+) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  IUJ45_RS04405 (IUJ45_04465) pilQ 845425..847734 (+) 2310 WP_002261352.1 type IV pilus secretin PilQ Machinery gene
  IUJ45_RS04410 (IUJ45_04470) - 848912..849424 (+) 513 WP_002222978.1 shikimate kinase -
  IUJ45_RS04415 (IUJ45_04475) aroB 849504..850583 (+) 1080 WP_002236907.1 3-dehydroquinate synthase -
  IUJ45_RS04420 (IUJ45_04480) - 851227..852069 (+) 843 WP_002222980.1 class II glutamine amidotransferase -
  IUJ45_RS04425 (IUJ45_04485) - 852098..852562 (+) 465 WP_002246402.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 769 a.a.        Molecular weight: 82493.08 Da        Isoelectric Point: 10.0982

>NTDB_id=501169 IUJ45_RS04405 WP_002261352.1 845425..847734(+) (pilQ) [Neisseria meningitidis strain PartJ-Nmeningitidis-RM8376]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQQAAAPAKQQAAAPAKQTNIDFRKDGKNAGII
ELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYF
TFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQ
ARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGS
VLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGF
GGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIAN
GGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNG
NTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2310 bp        

>NTDB_id=501169 IUJ45_RS04405 WP_002261352.1 845425..847734(+) (pilQ) [Neisseria meningitidis strain PartJ-Nmeningitidis-RM8376]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAACAGGCGGCGGCAC
CAGCAAAACAACAGGCGGCGGCACCAGCAAAACAAACCAATATCGATTTCCGCAAAGACGGCAAAAATGCCGGCATTATC
GAATTGGCGGCATTGGGCTTTGCCGGGCAGCCCGACATCAGCCAACAGCACGACCACATCATCGTTACGCTGAAAAACCA
TACCCTGCCGACCACGCTCCAACGCAGTTTGGATGTGGCAGACTTTAAAACACCGGTTCAAAAGGTTACGCTGAAACGCC
TCAATAACGACACCCAGCTGATTATCACAACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCGGATACTTT
ACCTTCCAAGTCCTGCCGAAAAAACAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACAGGCCGGAA
AATCTCCCTTGACTTCCAAGATGTCGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGGATGAACATTGTTG
CCAGCGACTCCGTCAACGGCAAAATGACCCTCTCCCTCAAAGACGTACCTTGGGATCAGGCTTTGGATTTGGTTATGCAG
GCACGCAACCTCGATATGCGCCAACAAGGGAACATCGTCAACATCGCGCCCCGCGACGAGCTGCTTGCCAAAGACAAAGC
CTTCTTACAGGCGGAAAAAGACATTGCCGATCTGGGCGCGCTGTATTCACAAAACTTCCAATTGAAATACAAAAATGTGG
AAGAATTCCGCAGCATCCTGCGTTTGGACAATGCCGACACAACCGGAAACCGCAATACGCTTGTCAGCGGCAGGGGCAGC
GTGCTGATCGATCCCGCCACCAATACCCTGATTGTTACCGATACCCGCAGCGTCATCGAAAAATTCCGCAAACTGATTGA
CGAATTGGACGTACCCGCGCAACAAGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCGCGATTTGG
GCGTTAAATTCGGCGCGACAGGCAAGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACTCCGGCTTC
GGCGGCGACGATAAATGGGGGGCCGAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATTTCGCTGGTGCG
CGCGATTTCCTCCGGTGCCTTGAATTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAACCAAAACGCTTGCCAATCCGC
GCGTGCTGACCCAAAACCGCAAAGAGGCCAAAATCGAATCTGGTTACGAAATTCCTTTCACCGTAACCTCAATCGCGAAC
GGCGGCAGCAGCACGAACACGGAACTCAAAAAAGCCGTCTTGGGGCTGACCGTTACGCCGAACATCACGCCCGACGGCCA
AATCATTATGACCGTCAAAATCAACAAGGACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATTCTGTGTATTTCGA
CCAAAAACCTGAATACGCAGGCTATGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAGACAACGGT
AATACGCTGACCAAAGTCCCCCTGTTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAAAAAACCGA
CCGCCGCGAACTGCTGATTTTCATTACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(444-515)

Bacterial type II and III secretion system protein (Secretin)

(601-760)

Secretin and TonB N terminus short domain (STN)

(371-416)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

99.74

100

0.997
  pilQ Neisseria meningitidis M1080

98.57

100

0.986
  pilQ Neisseria gonorrhoeae strain FA1090

91.417

100

0.914