Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ISN59_RS03250 Genome accession   NZ_CP063980
Coordinates   682346..683590 (+) Length   414 a.a.
NCBI ID   WP_010710870.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AR_0780     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 677346..688590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ISN59_RS03225 (ISN59_03215) - 678329..679121 (-) 793 Protein_605 hypothetical protein -
  ISN59_RS03230 (ISN59_03220) - 679285..679668 (+) 384 WP_002365398.1 YccF domain-containing protein -
  ISN59_RS03235 (ISN59_03225) - 679757..680182 (+) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  ISN59_RS03240 (ISN59_03230) - 680241..680870 (+) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  ISN59_RS03245 (ISN59_03235) - 680949..682154 (-) 1206 WP_002360981.1 hypothetical protein -
  ISN59_RS03250 (ISN59_03240) cinA 682346..683590 (+) 1245 WP_010710870.1 competence/damage-inducible protein A Machinery gene
  ISN59_RS03255 (ISN59_03245) recA 683704..684750 (+) 1047 WP_002354860.1 recombinase RecA Machinery gene
  ISN59_RS03260 (ISN59_03250) rny 685147..686703 (+) 1557 WP_002354863.1 ribonuclease Y -
  ISN59_RS03265 (ISN59_03255) - 686863..687660 (+) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  ISN59_RS03270 (ISN59_03260) - 687734..688120 (+) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45193.29 Da        Isoelectric Point: 4.6698

>NTDB_id=498256 ISN59_RS03250 WP_010710870.1 682346..683590(+) (cinA) [Enterococcus faecalis strain AR_0780]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=498256 ISN59_RS03250 WP_010710870.1 682346..683590(+) (cinA) [Enterococcus faecalis strain AR_0780]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGGCAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437