Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SPNOXC_RS09960 Genome accession   NC_017592
Coordinates   1833917..1834933 (-) Length   338 a.a.
NCBI ID   WP_074017570.1    Uniprot ID   -
Organism   Streptococcus pneumoniae OXC141     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1828917..1839933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNOXC_RS13370 - 1828994..1829125 (-) 132 WP_000768904.1 hypothetical protein -
  SPNOXC_RS09915 (SPNOXC18000) - 1829126..1830316 (-) 1191 WP_000167765.1 acetate kinase -
  SPNOXC_RS09920 (SPNOXC18010) comYH 1830367..1831320 (-) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  SPNOXC_RS12020 (SPNOXC18020) - 1831381..1831975 (-) 595 Protein_1876 methyltransferase domain-containing protein -
  SPNOXC_RS09935 (SPNOXC18030) comGG/cglG 1832112..1832525 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPNOXC_RS09940 (SPNOXC18040) comGF/cglF 1832503..1832964 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPNOXC_RS09945 (SPNOXC18050) comGE/cglE 1832927..1833229 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPNOXC_RS09950 (SPNOXC18060) comGD/cglD 1833192..1833596 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPNOXC_RS09955 (SPNOXC18070) comGC/cglC 1833589..1833915 (-) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  SPNOXC_RS09960 (SPNOXC18080) comGB/cglB 1833917..1834933 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPNOXC_RS09965 (SPNOXC18090) comGA/cglA/cilD 1834881..1835822 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  SPNOXC_RS09970 (SPNOXC18100) - 1835898..1836263 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPNOXC_RS09975 (SPNOXC18110) - 1836414..1837472 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  SPNOXC_RS09980 (SPNOXC18120) nagA 1837635..1838786 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38482.48 Da        Isoelectric Point: 9.6162

>NTDB_id=49273 SPNOXC_RS09960 WP_074017570.1 1833917..1834933(-) (comGB/cglB) [Streptococcus pneumoniae OXC141]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=49273 SPNOXC_RS09960 WP_074017570.1 1833917..1834933(-) (comGB/cglB) [Streptococcus pneumoniae OXC141]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment