Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   IF751_RS02550 Genome accession   NZ_CP062407
Coordinates   545395..545964 (+) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain NAS_NP_181     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 540395..550964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF751_RS02520 (IF751_02505) - 540452..540571 (-) 120 WP_228766517.1 hypothetical protein -
  IF751_RS02525 (IF751_02510) - 540807..542453 (-) 1647 WP_061811726.1 IS1182-like element ISSau3 family transposase -
  IF751_RS02530 (IF751_02515) - 542908..543510 (-) 603 WP_001033867.1 CPBP family glutamic-type intramembrane protease -
  IF751_RS02535 (IF751_02520) - 543525..543701 (-) 177 WP_000214898.1 YkvS family protein -
  IF751_RS02540 (IF751_02525) - 543900..544886 (+) 987 WP_000668820.1 lipoate--protein ligase -
  IF751_RS02545 (IF751_02530) - 544967..545185 (-) 219 WP_000876826.1 IDEAL domain-containing protein -
  IF751_RS02550 (IF751_02535) comK/comK1 545395..545964 (+) 570 WP_000287265.1 competence protein ComK Regulator
  IF751_RS02565 (IF751_02550) - 546453..547964 (-) 1512 WP_042908661.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  IF751_RS02570 (IF751_02555) - 548103..549461 (-) 1359 WP_000021872.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=489512 IF751_RS02550 WP_000287265.1 545395..545964(+) (comK/comK1) [Staphylococcus aureus strain NAS_NP_181]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=489512 IF751_RS02550 WP_000287265.1 545395..545964(+) (comK/comK1) [Staphylococcus aureus strain NAS_NP_181]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGCGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATCACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTATATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1