Detailed information NTG0488841

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF704_RS10660
• Genome accession: NZ_CP062380
• Coordinates: 2174444..2175331 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_076
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2169444..2180331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF704_RS10630 (IF704_10510)	-	2170176..2170937 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
IF704_RS10635 (IF704_10515)	-	2171182..2171637 (+)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF704_RS14400	-	2171759..2171860 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF704_RS10645 (IF704_10525)	-	2171920..2173344 (-)	1425	WP_047213011.1	alkaline phosphatase	-
IF704_RS10650 (IF704_10530)	-	2173542..2173742 (+)	201	WP_000604725.1	hypothetical protein	-
IF704_RS10655 (IF704_10535)	braR	2173768..2174433 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF704_RS10660 (IF704_10540)	braS	2174444..2175331 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF704_RS10665 (IF704_10545)	-	2175439..2176194 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
IF704_RS10670 (IF704_10550)	-	2176191..2178191 (+)	2001	WP_042907889.1	ABC transporter permease	-
IF704_RS10675 (IF704_10555)	-	2178856..2178969 (+)	114	WP_072357681.1	hypothetical protein	-
IF704_RS10680 (IF704_10560)	-	2179351..2179611 (+)	261	WP_240022112.1	hypothetical protein	-
IF704_RS10685 (IF704_10565)	-	2179621..2180118 (+)	498	WP_001065267.1	glutathione peroxidase	-
IF704_RS10690 (IF704_10570)	-	2180226..2180318 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=488841 IF704_RS10660 WP_000143420.1 2174444..2175331(+) (braS) [Staphylococcus aureus strain NAS_AN_076]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488841 IF704_RS10660 WP_000143420.1 2174444..2175331(+) (braS) [Staphylococcus aureus strain NAS_AN_076]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993