Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   IF742_RS02365 Genome accession   NZ_CP062340
Coordinates   441978..442277 (+) Length   99 a.a.
NCBI ID   WP_000844413.1    Uniprot ID   X5E258
Organism   Staphylococcus aureus strain NAS_AN_275     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 436978..447277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF742_RS02325 (IF742_02325) - 437039..437242 (+) 204 WP_000087561.1 YqgQ family protein -
  IF742_RS02330 (IF742_02330) - 437239..438225 (+) 987 WP_000161314.1 ROK family glucokinase -
  IF742_RS02335 (IF742_02335) - 438225..438554 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  IF742_RS02340 (IF742_02340) - 438551..439174 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  IF742_RS02345 (IF742_02345) comGA 439226..440200 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  IF742_RS02350 (IF742_02350) comGB 440172..441242 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  IF742_RS02355 (IF742_02355) comGC 441256..441567 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  IF742_RS02360 (IF742_02360) comGD 441545..441991 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  IF742_RS02365 (IF742_02365) comGE 441978..442277 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  IF742_RS02370 (IF742_02370) comGF 442195..442692 (+) 498 WP_029642894.1 competence type IV pilus minor pilin ComGF Machinery gene
  IF742_RS02375 (IF742_02375) - 442789..442935 (+) 147 WP_001789879.1 hypothetical protein -
  IF742_RS02380 (IF742_02380) - 442925..443449 (+) 525 WP_001015119.1 shikimate kinase -
  IF742_RS02385 (IF742_02385) gcvT 443608..444699 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  IF742_RS02390 (IF742_02390) gcvPA 444719..446065 (+) 1347 WP_000019687.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 99 a.a.        Molecular weight: 11093.20 Da        Isoelectric Point: 9.9215

>NTDB_id=488029 IF742_RS02365 WP_000844413.1 441978..442277(+) (comGE) [Staphylococcus aureus strain NAS_AN_275]
MKSYKCKGSFLIDSMAGFLLIGLITLLLIPMMNQMQASINHKLQTIDASKVILTTVSKINKEELKKGVTIGKYDIKQSDQ
QICAISKNTTSYQKTCIQY

Nucleotide


Download         Length: 300 bp        

>NTDB_id=488029 IF742_RS02365 WP_000844413.1 441978..442277(+) (comGE) [Staphylococcus aureus strain NAS_AN_275]
ATGAAAAGCTATAAGTGTAAAGGATCATTCTTAATAGATAGTATGGCTGGATTTTTGCTAATTGGATTGATTACATTACT
ATTGATACCAATGATGAATCAAATGCAAGCGAGTATAAACCATAAACTACAAACAATTGATGCTTCTAAAGTAATTTTGA
CGACTGTATCTAAAATTAATAAAGAAGAACTTAAGAAGGGGGTAACTATAGGGAAGTATGATATTAAGCAAAGTGACCAA
CAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB X5E258

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Staphylococcus aureus MW2

86.842

100

1

  comGE Staphylococcus aureus N315

98.99

100

0.99