Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   IAU62_RS06655 Genome accession   NZ_CP061029
Coordinates   1359860..1360489 (-) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0132     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1354860..1365489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAU62_RS06625 - 1355252..1355782 (-) 531 WP_002447436.1 acyl-CoA thioesterase -
  IAU62_RS06630 - 1355863..1357104 (-) 1242 WP_099774840.1 aminopeptidase -
  IAU62_RS06635 - 1357106..1357321 (-) 216 WP_001830421.1 DUF1128 domain-containing protein -
  IAU62_RS06640 - 1357463..1357927 (+) 465 WP_002458546.1 low molecular weight protein-tyrosine-phosphatase -
  IAU62_RS06645 - 1357935..1358219 (+) 285 WP_002447438.1 YtxH domain-containing protein -
  IAU62_RS06650 - 1358625..1359803 (+) 1179 WP_002458547.1 YihY/virulence factor BrkB family protein -
  IAU62_RS06655 vraR 1359860..1360489 (-) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  IAU62_RS06660 vraS 1360479..1361525 (-) 1047 WP_002447441.1 sensor histidine kinase Regulator
  IAU62_RS06665 liaF 1361522..1362223 (-) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  IAU62_RS06670 - 1362238..1362624 (-) 387 WP_162153127.1 hypothetical protein -
  IAU62_RS06675 map 1362782..1363537 (-) 756 WP_002447444.1 type I methionyl aminopeptidase -
  IAU62_RS06680 - 1363711..1364697 (+) 987 WP_002447445.1 aromatic acid exporter family protein -
  IAU62_RS06685 - 1364850..1365386 (-) 537 WP_099774844.1 hypothetical protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=479870 IAU62_RS06655 WP_002473914.1 1359860..1360489(-) (vraR) [Staphylococcus epidermidis strain Z0118SE0132]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=479870 IAU62_RS06655 WP_002473914.1 1359860..1360489(-) (vraR) [Staphylococcus epidermidis strain Z0118SE0132]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373