Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | H7X60_RS00615 | Genome accession | NZ_CP060266 |
| Coordinates | 99559..100512 (+) | Length | 317 a.a. |
| NCBI ID | WP_010921802.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain SP1450 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 94559..105512
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7X60_RS00575 (H7X60_00575) | - | 95386..95751 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| H7X60_RS00580 (H7X60_00580) | comYA | 95844..96782 (+) | 939 | WP_010921798.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| H7X60_RS00585 (H7X60_00585) | comYB | 96718..97752 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| H7X60_RS00590 (H7X60_00590) | comYC | 97754..98080 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| H7X60_RS00595 (H7X60_00595) | comGD | 98055..98483 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| H7X60_RS00600 (H7X60_00600) | comGE | 98440..98724 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| H7X60_RS00605 (H7X60_00605) | comYF | 98717..99151 (+) | 435 | WP_010921800.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| H7X60_RS00610 (H7X60_00610) | comGG | 99135..99461 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| H7X60_RS00615 (H7X60_00615) | comYH | 99559..100512 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| H7X60_RS00620 (H7X60_00620) | - | 100571..101767 (+) | 1197 | WP_010921803.1 | acetate kinase | - |
| H7X60_RS00625 (H7X60_00625) | - | 101954..102262 (+) | 309 | WP_010921804.1 | hypothetical protein | - |
| H7X60_RS00630 (H7X60_00630) | proC | 102345..103115 (-) | 771 | WP_010921805.1 | pyrroline-5-carboxylate reductase | - |
| H7X60_RS00635 (H7X60_00635) | pepA | 103163..104230 (-) | 1068 | WP_010921806.1 | glutamyl aminopeptidase | - |
| H7X60_RS00640 (H7X60_00640) | - | 104695..104979 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| H7X60_RS00645 (H7X60_00645) | - | 104976..105293 (+) | 318 | WP_011285355.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.10 Da Isoelectric Point: 4.7205
>NTDB_id=474813 H7X60_RS00615 WP_010921802.1 99559..100512(+) (comYH) [Streptococcus pyogenes strain SP1450]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=474813 H7X60_RS00615 WP_010921802.1 99559..100512(+) (comYH) [Streptococcus pyogenes strain SP1450]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comYH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |