Detailed information NTG0443454

Bioinformatically predicted

Overview

• Name: stkP
• Type: Regulator
• Locus tag: HKM25_RS08650
• Genome accession: NZ_CP053210
• Coordinates: 1694218..1696197 (-)
• Length: 659 a.a.
• NCBI ID: WP_000614540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6A-10
• Function: require for competence development; phosphorylate ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1689218..1701197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKM25_RS08620 (HKM25_1762)	-	1689313..1690587 (-)	1275	WP_000704388.1	hydroxymethylglutaryl-CoA reductase, degradative	-
HKM25_RS08625 (HKM25_1763)	-	1690587..1691759 (-)	1173	WP_000151959.1	hydroxymethylglutaryl-CoA synthase	-
HKM25_RS08630 (HKM25_1764)	-	1691890..1692138 (-)	249	WP_001821065.1	hypothetical protein	-
HKM25_RS08635	-	1692206..1692832 (-)	627	Protein_1725	transposase	-
HKM25_RS08640 (HKM25_1767)	-	1692894..1693343 (-)	450	WP_000176924.1	threonine/serine exporter family protein	-
HKM25_RS08645 (HKM25_1768)	-	1693345..1694103 (-)	759	WP_000392885.1	threonine/serine exporter ThrE family protein	-
HKM25_RS08650 (HKM25_1769)	stkP	1694218..1696197 (-)	1980	WP_000614540.1	serine/threonine-protein kinase StkP	Regulator
HKM25_RS08655 (HKM25_1770)	-	1696194..1696934 (-)	741	WP_000406247.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
HKM25_RS08660 (HKM25_1771)	rsmB	1696949..1698262 (-)	1314	WP_001809725.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
HKM25_RS08665 (HKM25_1772)	fmt	1698255..1699190 (-)	936	WP_000163688.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 659 a.a.
• Molecular weight: 72316.86 Da
• Isoelectric Point: 9.0945

>NTDB_id=443454 HKM25_RS08650 WP_000614540.1 1694218..1696197(-) (stkP) [Streptococcus pneumoniae strain 6A-10]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide

• Length: 1980 bp

>NTDB_id=443454 HKM25_RS08650 WP_000614540.1 1694218..1696197(-) (stkP) [Streptococcus pneumoniae strain 6A-10]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCAGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACGGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTATCGCTCGGTTTCAGAGATGTATGT
AGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
TAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCGAATGAAAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTA
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-227)

• PASTA domain (PASTA) (440-505)

• PASTA domain (PASTA) (582-651)

• PASTA domain (PASTA) (513-577)

• PASTA domain (PASTA) (371-432)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
stkP	Streptococcus pneumoniae TIGR4	99.848	100	0.998
stkP	Streptococcus pneumoniae D39	99.697	100	0.997
stkP	Streptococcus pneumoniae R6	99.697	100	0.997
stkP	Streptococcus pneumoniae Rx1	99.545	100	0.995
pknB	Streptococcus mutans UA159	52.65	88.771	0.467
stkP/pknB	Streptococcus salivarius strain HSISS4	51.807	88.164	0.457