Detailed information    

insolico Bioinformatically predicted

Overview

Name   HI0659   Type   Machinery gene
Locus tag   HKM25_RS02810 Genome accession   NZ_CP053210
Coordinates   541247..541513 (+) Length   88 a.a.
NCBI ID   WP_001814186.1    Uniprot ID   A0A654WS02
Organism   Streptococcus pneumoniae strain 6A-10     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 540675..541124 541247..541513 flank 123


Gene organization within MGE regions


Location: 540675..541513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS02805 (HKM25_573) - 540675..541121 (+) 447 Protein_560 IS30 family transposase -
  HKM25_RS02810 (HKM25_574) HI0659 541247..541513 (+) 267 WP_001814186.1 helix-turn-helix transcriptional regulator Machinery gene

Sequence

Protein


Download         Length: 88 a.a.        Molecular weight: 9641.11 Da        Isoelectric Point: 4.2720

>NTDB_id=443429 HKM25_RS02810 WP_001814186.1 541247..541513(+) (HI0659) [Streptococcus pneumoniae strain 6A-10]
MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEVSGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAV
VPLEQGKS

Nucleotide


Download         Length: 267 bp        

>NTDB_id=443429 HKM25_RS02810 WP_001814186.1 541247..541513(+) (HI0659) [Streptococcus pneumoniae strain 6A-10]
TTGGAAGGATGTCCATCTGAGCTCTTTAGCAAGGAGGAAATCCTTGAAAGTGATATGCGAGTGGCTATCATGAGCGAGTT
GATTGAGGCTAGGTATGAACAAGGAATCAGTCAGAAAAAGCTGGAAGAAGTCAGTGGAATAAGCCAGCCTGTCATAGCTA
GGATGGAGACAGGAGAGAGCAGTCTTCAGTTGGATACGGTCTTAAAAGTTCTAACCAGTCTAGGAAAGACACTAGCAGTC
GTTCCACTTGAACAGGGGAAAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(29-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A654WS02

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  HI0659 Haemophilus influenzae Rd KW20

55.844

87.5

0.489