Detailed information NTG0043545

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: MI1_RS00415
• Genome accession: NC_016805
• Coordinates: 71690..73837 (-)
• Length: 715 a.a.
• NCBI ID: WP_014324156.1
• Uniprot ID: -
• Organism: Leuconostoc mesenteroides subsp. mesenteroides J18
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 66690..78837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MI1_RS00400 (MI1_00295)	-	67884..68471 (+)	588	WP_014324154.1	helix-turn-helix domain-containing protein	-
MI1_RS00405 (MI1_00300)	-	68529..69266 (+)	738	WP_002815471.1	SDR family NAD(P)-dependent oxidoreductase	-
MI1_RS10775	-	69382..69507 (+)	126	WP_011679061.1	putative metal homeostasis protein	-
MI1_RS00410 (MI1_00310)	-	70323..71672 (-)	1350	WP_014324155.1	bacteriocin secretion accessory protein	-
MI1_RS00415 (MI1_00315)	comA	71690..73837 (-)	2148	WP_014324156.1	peptide cleavage/export ABC transporter	Regulator
MI1_RS10535	-	74068..74244 (+)	177	WP_010287032.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
MI1_RS10540	-	74275..74436 (+)	162	WP_010287029.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
MI1_RS10545	-	74895..75032 (+)	138	WP_014324157.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
MI1_RS00425 (MI1_00340)	-	75047..75226 (+)	180	WP_010287277.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
MI1_RS10550	-	75388..75564 (+)	177	WP_010287275.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
MI1_RS10805	-	75849..76019 (+)	171	WP_014324158.1	hypothetical protein	-
MI1_RS00430 (MI1_00355)	-	76025..76237 (+)	213	WP_011679067.1	hypothetical protein	-
MI1_RS00435 (MI1_00360)	-	76510..77235 (-)	726	WP_011679068.1	response regulator transcription factor	-
MI1_RS00440 (MI1_00365)	-	77241..78551 (-)	1311	WP_014324159.1	GHKL domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80253.23 Da
• Isoelectric Point: 9.2488

>NTDB_id=43545 MI1_RS00415 WP_014324156.1 71690..73837(-) (comA) [Leuconostoc mesenteroides subsp. mesenteroides J18]
MRKFHYISQLEEKDCGVAALAMILKRHGSDVSLANIRERCQTSLSGTTALGLVKAAESFNMDVRPIQADLTLFDMKDLPL
PFIAHVEKKGQYLHYYVVYGFTKNKVIIADPDPTVAKTAMTLQEFSKEWTGVALFMSPSPRYKPFKENKNSILSFLPIIS
RQKGLIANIVVASLLVTLISIAGSYYMQLVIDAHIPSAMSNTLTVVSLGLIATYVLQQLLSFARTYLLTIMGQRLSIEVI
LSYIRHLFELPVNFFATRRTGEIVTRFNDANTIIDAMANTILSLFLDLGITIIVGSVLAIQNTKLFLLSLISFPIYFLIV
YCFMKPFERLNQEQMASNATLSSSIIEDINGIETIKSLTSEKTSYQKIDREFVDYLKKSFAHQKSEAIQNSIKQATQLII
NVLVLWLGAKLVISNQISVGQLVTYNALLGYFTEPFQNIINLQAKLQTATVANRRLNEVYLVKSEFKKSESQELHHNNPH
NIIVDDVSYQYGYQKNILHHFSIKIPFGEKIALVGVSGSGKSTLAKLLVHFISPSAGNIFIGEQNIKHVQRQNLRQHILY
LPQNPYIFTGSILDNLTLGARENTTQEDILHAVELADIKDDIENMPQSYQTGISEEGGMSGGQKQRIALARALLSNSQIL
ILDESTSNLDVATEKKIIDNLLSLKNKTIIFIAHRLTIAEKVQRVILLEKGIISEDGSHAELIHKKSKYYHLVKH

Nucleotide

• Length: 2148 bp

>NTDB_id=43545 MI1_RS00415 WP_014324156.1 71690..73837(-) (comA) [Leuconostoc mesenteroides subsp. mesenteroides J18]
ATGAGAAAGTTTCATTATATATCACAACTTGAAGAAAAAGATTGTGGCGTAGCAGCACTAGCTATGATTTTAAAGCGACA
CGGCTCAGATGTTTCATTAGCTAACATTCGTGAACGCTGTCAAACATCCTTATCGGGTACAACGGCGCTAGGCTTAGTGA
AGGCCGCTGAATCATTCAATATGGATGTCCGTCCTATTCAAGCTGACCTTACCTTATTCGACATGAAAGATTTACCTCTG
CCGTTCATCGCTCATGTTGAGAAAAAAGGTCAATATTTGCATTATTATGTAGTGTACGGATTCACTAAAAACAAAGTTAT
CATTGCAGATCCAGATCCAACAGTTGCTAAAACCGCAATGACGTTACAAGAATTCTCTAAAGAGTGGACTGGTGTAGCAT
TGTTCATGTCGCCTTCACCCAGATATAAACCTTTTAAAGAAAATAAAAACAGTATCCTATCCTTTCTGCCAATTATTAGT
CGACAAAAAGGATTAATTGCTAATATTGTCGTCGCTTCTTTGCTAGTCACTTTAATTAGTATCGCTGGCTCTTATTATAT
GCAACTAGTGATTGATGCTCATATTCCTAGTGCTATGTCTAACACATTAACCGTTGTTTCATTAGGACTCATTGCCACCT
ATGTGTTACAACAGCTACTTAGTTTTGCTCGCACCTATCTGTTAACTATTATGGGACAACGATTATCGATTGAAGTCATA
CTATCATACATACGGCACTTGTTCGAATTACCTGTTAATTTCTTTGCCACACGTCGAACAGGTGAAATTGTCACGCGTTT
TAATGACGCCAACACCATTATTGATGCCATGGCAAATACAATTCTCTCACTTTTTTTAGATTTAGGTATCACGATAATTG
TTGGCAGCGTCTTAGCAATTCAAAATACAAAACTTTTTCTGCTATCTCTAATCTCTTTTCCTATCTACTTCTTGATTGTC
TATTGTTTCATGAAGCCATTTGAACGATTGAATCAAGAACAGATGGCAAGTAATGCAACGCTGAGCTCATCTATTATTGA
AGACATCAATGGTATTGAAACCATAAAATCTTTGACAAGCGAGAAGACGAGCTACCAAAAAATTGATCGTGAATTTGTCG
ATTATTTAAAAAAATCCTTTGCCCATCAAAAAAGCGAAGCCATTCAAAATAGTATTAAACAAGCAACTCAACTCATTATC
AATGTGCTCGTTTTATGGTTGGGTGCCAAGCTAGTGATTAGTAATCAAATTAGTGTCGGTCAGTTAGTTACCTATAATGC
ATTACTAGGCTACTTTACTGAACCTTTCCAAAATATTATTAACTTGCAGGCGAAATTACAAACGGCAACGGTTGCTAACC
GACGATTAAACGAAGTCTATCTTGTAAAATCAGAGTTTAAAAAATCAGAATCACAAGAGCTTCATCATAACAACCCTCAT
AACATTATAGTTGACGACGTCAGCTATCAATATGGTTATCAAAAGAACATATTACACCACTTTTCAATTAAGATCCCCTT
TGGTGAAAAAATTGCTCTGGTCGGTGTTAGCGGTTCCGGTAAGTCAACATTAGCCAAACTACTTGTTCATTTTATATCTC
CTAGTGCTGGCAACATTTTTATTGGTGAACAAAACATTAAACACGTTCAACGACAAAATTTAAGGCAACATATTCTTTAT
CTACCACAAAACCCATACATATTTACTGGAAGCATATTAGATAATTTAACACTAGGTGCTCGTGAAAACACAACACAAGA
AGACATCCTACATGCTGTTGAGCTTGCTGACATTAAAGATGACATCGAAAATATGCCACAAAGTTATCAAACCGGAATTT
CAGAGGAAGGCGGCATGTCTGGAGGCCAAAAGCAGCGTATCGCTTTAGCTAGAGCCCTCCTTAGTAATTCTCAAATACTT
ATTTTGGATGAATCAACCAGTAATCTTGATGTCGCAACTGAAAAAAAGATTATTGATAATTTATTATCGCTTAAAAATAA
AACAATCATTTTTATTGCACATCGCCTGACTATTGCTGAAAAAGTCCAACGCGTTATTCTGCTTGAAAAAGGGATCATCA
GTGAAGATGGTAGCCATGCTGAACTTATACATAAAAAATCAAAATACTATCATCTTGTAAAGCATTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (168-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	59.664	99.86	0.596
comA	Streptococcus mitis NCTC 12261	58.006	99.58	0.578
comA	Streptococcus mitis SK321	57.725	99.58	0.575
comA	Streptococcus pneumoniae Rx1	57.444	99.58	0.572
comA	Streptococcus pneumoniae D39	57.444	99.58	0.572
comA	Streptococcus pneumoniae R6	57.444	99.58	0.572
comA	Streptococcus pneumoniae TIGR4	57.163	99.58	0.569
comA/nlmT	Streptococcus mutans UA159	54.149	99.441	0.538