Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   WPAWT_RS23560 Genome accession   NZ_CP049161
Coordinates   5106521..5107858 (+) Length   445 a.a.
NCBI ID   WP_003094694.1    Uniprot ID   A0A0H2ZG94
Organism   Pseudomonas aeruginosa strain MS14403     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5101521..5112858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WPAWT_RS23535 (WPAWT_04700) pgeF 5101664..5102392 (-) 729 WP_003112833.1 peptidoglycan editing factor PgeF -
  WPAWT_RS23540 (WPAWT_04701) rluD 5102389..5103351 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  WPAWT_RS23545 (WPAWT_04702) - 5103497..5104522 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  WPAWT_RS23550 (WPAWT_04703) - 5104679..5104924 (+) 246 WP_003102591.1 PP0621 family protein -
  WPAWT_RS23555 (WPAWT_04704) pilS 5104914..5106506 (+) 1593 WP_003123394.1 two-component system sensor histidine kinase PilS Regulator
  WPAWT_RS23560 (WPAWT_04705) pilR 5106521..5107858 (+) 1338 WP_003094694.1 two-component system response regulator PilR Regulator
  WPAWT_RS23565 (WPAWT_04706) thiO 5107904..5108998 (-) 1095 WP_023122775.1 glycine oxidase ThiO -
  WPAWT_RS23570 (WPAWT_04707) - 5109138..5109638 (+) 501 WP_016562346.1 GspH/FimT family pseudopilin -
  WPAWT_RS23575 (WPAWT_04708) - 5109761..5110249 (+) 489 WP_003141552.1 GspH/FimT family pseudopilin -
  WPAWT_RS23580 (WPAWT_04709) pilV 5110259..5110783 (+) 525 WP_003116261.1 type IV pilus modification protein PilV Machinery gene
  WPAWT_RS23585 (WPAWT_04710) - 5110792..5111607 (+) 816 WP_016562347.1 PilW family protein -
  WPAWT_RS23590 (WPAWT_04711) - 5111604..5112209 (+) 606 WP_003116263.1 PilX N-terminal domain-containing pilus assembly protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49737.06 Da        Isoelectric Point: 5.8654

>NTDB_id=425063 WPAWT_RS23560 WP_003094694.1 5106521..5107858(+) (pilR) [Pseudomonas aeruginosa strain MS14403]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=425063 WPAWT_RS23560 WP_003094694.1 5106521..5107858(+) (pilR) [Pseudomonas aeruginosa strain MS14403]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZG94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

100

100

1
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384