Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E3T04_RS12580 Genome accession   NZ_CP047782
Coordinates   2471484..2472149 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain UP_1352     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2466484..2477149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T04_RS12560 (E3T04_12560) - 2466954..2467067 (-) 114 WP_031918517.1 hypothetical protein -
  E3T04_RS12565 (E3T04_12565) - 2467726..2469726 (-) 2001 WP_000776748.1 ABC transporter permease -
  E3T04_RS12570 (E3T04_12570) - 2469723..2470478 (-) 756 WP_000923769.1 ABC transporter ATP-binding protein -
  E3T04_RS12575 (E3T04_12575) braS 2470586..2471473 (-) 888 WP_000143430.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E3T04_RS12580 (E3T04_12580) braR 2471484..2472149 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E3T04_RS12585 (E3T04_12585) - 2472175..2472375 (-) 201 WP_000604725.1 hypothetical protein -
  E3T04_RS12590 (E3T04_12590) - 2472573..2473996 (+) 1424 Protein_2456 alkaline phosphatase -
  E3T04_RS15160 - 2474056..2474157 (-) 102 WP_000731972.1 SE2200 family small protein -
  E3T04_RS12600 (E3T04_12600) - 2474279..2474734 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E3T04_RS12605 (E3T04_12605) - 2474975..2475736 (-) 762 WP_000323452.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=415983 E3T04_RS12580 WP_000697883.1 2471484..2472149(-) (braR) [Staphylococcus aureus strain UP_1352]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=415983 E3T04_RS12580 WP_000697883.1 2471484..2472149(-) (braR) [Staphylococcus aureus strain UP_1352]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAGCCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment