Detailed information NTG0041071

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SGPB_RS02995
• Genome accession: NC_015600
• Coordinates: 562116..564347 (+)
• Length: 743 a.a.
• NCBI ID: WP_013851601.1
• Uniprot ID: F5X5G2
• Organism: Streptococcus pasteurianus ATCC 43144
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 557116..569347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGPB_RS02965 (SGPB_0536)	-	557766..558626 (+)	861	WP_003063816.1	helix-turn-helix transcriptional regulator	-
SGPB_RS02970 (SGPB_0537)	-	558631..559260 (+)	630	WP_013851599.1	ROK family protein	-
SGPB_RS02975 (SGPB_0538)	-	559492..559773 (-)	282	WP_003063819.1	GIY-YIG nuclease family protein	-
SGPB_RS02980 (SGPB_0539)	-	559748..560509 (-)	762	WP_003063822.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SGPB_RS02985 (SGPB_0540)	-	560617..561363 (+)	747	WP_003063827.1	lysophospholipid acyltransferase family protein	-
SGPB_RS02990 (SGPB_0541)	comEA	561458..562123 (+)	666	WP_013851600.1	helix-hairpin-helix domain-containing protein	Machinery gene
SGPB_RS02995 (SGPB_0542)	comEC/celB	562116..564347 (+)	2232	WP_013851601.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SGPB_RS03000 (SGPB_0543)	holA	564420..565457 (+)	1038	WP_043910377.1	DNA polymerase III subunit delta	-
SGPB_RS03005 (SGPB_0544)	sodA	565546..566154 (+)	609	WP_013851603.1	superoxide dismutase SodA	-
SGPB_RS03010 (SGPB_0545)	-	566303..567028 (+)	726	WP_013851604.1	YebC/PmpR family DNA-binding transcriptional regulator	-
SGPB_RS03015 (SGPB_0546)	queA	567060..568088 (-)	1029	WP_003063841.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
SGPB_RS03020 (SGPB_0547)	-	568264..568764 (+)	501	WP_003063844.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83871.18 Da
• Isoelectric Point: 8.0695

>NTDB_id=41071 SGPB_RS02995 WP_013851601.1 562116..564347(+) (comEC/celB) [Streptococcus pasteurianus ATCC 43144]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLTCFAVFFLTKANQTEQAYQAAPD
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLSQTVVLSGDMDLEEATPQRNFDGFDYRTYLKH
EGIYRVVNLSAINNVELVHKTTLWDKLHDVRRKAIVSIQQHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLHLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTMGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKHTKAILGGPIVFGKPNLGILVLLFLMLGVLYDCWRRKKTAIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGNTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRVQNMTI
YRTDEQGAIRFRGLNYWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=41071 SGPB_RS02995 WP_013851601.1 562116..564347(+) (comEC/celB) [Streptococcus pasteurianus ATCC 43144]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GCTTGTGTTTAACCTGTTTTGCGGTATTTTTTCTGACTAAGGCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGAT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAGTCAAACGGTTGTTT
TATCTGGTGATATGGATTTGGAAGAAGCAACGCCCCAGCGGAATTTTGATGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGTATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTCATAAGACGACTTTGTGGGATAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCAGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTTGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACATCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTAATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTTATAGTTATGCCAAAT
TTTCTGCTGACGATGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACCGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGCACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGTAAACCAAATCTTGGTATCTTGGTGCTACTATTTTTAATGTTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAACGGCAATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGAATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTAGAGGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTGTTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTACCAGTTGATGT
CTTAAAAGCAGGGCATCATGGCTCAAAAGGATCATCAAGTTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGTTACAAACATCCTCACCAAGAAACGCTTGAACGCTTCCGAGTACAAAACATGACCATT
TACCGCACAGACGAGCAAGGCGCTATCCGCTTTAGAGGACTAAATTACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

• Competence protein (Competence) (213-459)

3D structure

• AlphaFold DB: F5X5G2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.695	99.865	0.526
comEC/celB	Streptococcus mitis SK321	52.156	99.865	0.521
comEC/celB	Streptococcus pneumoniae TIGR4	51.144	100	0.511
comEC/celB	Streptococcus pneumoniae Rx1	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae D39	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae R6	50.606	100	0.506
comEC	Lactococcus lactis subsp. cremoris KW2	47.51	100	0.475