Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | GO593_RS10660 | Genome accession | NZ_CP046654 |
| Coordinates | 2237803..2238921 (-) | Length | 372 a.a. |
| NCBI ID | WP_000347036.1 | Uniprot ID | A0A009PAD6 |
| Organism | Acinetobacter baumannii strain ATCC 19606 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2202344..2269496 | 2237803..2238921 | within | 0 |
Gene organization within MGE regions
Location: 2202344..2269496
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GO593_RS10485 (GO593_10485) | - | 2202745..2203305 (-) | 561 | WP_001048354.1 | hypothetical protein | - |
| GO593_RS10490 (GO593_10490) | - | 2203396..2204256 (-) | 861 | WP_000838088.1 | pirin family protein | - |
| GO593_RS10495 (GO593_10495) | hemJ | 2204427..2204879 (-) | 453 | WP_000339889.1 | protoporphyrinogen oxidase HemJ | - |
| GO593_RS10500 (GO593_10500) | - | 2204898..2206127 (-) | 1230 | WP_000832710.1 | beta-ketoacyl-ACP synthase II | - |
| GO593_RS10505 (GO593_10505) | - | 2206424..2207749 (+) | 1326 | WP_000160010.1 | EcsC family protein | - |
| GO593_RS10510 (GO593_10510) | rpsL | 2207950..2208324 (+) | 375 | WP_000246374.1 | 30S ribosomal protein S12 | - |
| GO593_RS10515 (GO593_10515) | rpsG | 2208484..2208954 (+) | 471 | WP_001138055.1 | 30S ribosomal protein S7 | - |
| GO593_RS10520 (GO593_10520) | fusA | 2209133..2211271 (+) | 2139 | WP_000113824.1 | elongation factor G | - |
| GO593_RS10525 (GO593_10525) | tuf | 2211366..2212556 (+) | 1191 | WP_001029610.1 | elongation factor Tu | - |
| GO593_RS10530 (GO593_10530) | - | 2212760..2213641 (+) | 882 | WP_000992301.1 | metal-dependent hydrolase | - |
| GO593_RS10535 (GO593_10535) | - | 2213878..2214753 (+) | 876 | WP_000992291.1 | metal-dependent hydrolase | - |
| GO593_RS10540 (GO593_10540) | rimI | 2214861..2215316 (+) | 456 | WP_000621546.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| GO593_RS10545 (GO593_10545) | - | 2215361..2216176 (-) | 816 | WP_000844343.1 | arginyltransferase | - |
| GO593_RS10550 (GO593_10550) | aat | 2216195..2216926 (-) | 732 | WP_000854789.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
| GO593_RS10555 (GO593_10555) | trxB | 2217047..2217994 (-) | 948 | WP_001276144.1 | thioredoxin-disulfide reductase | - |
| GO593_RS10560 (GO593_10560) | - | 2218264..2221296 (+) | 3033 | WP_000127835.1 | DNA translocase FtsK | - |
| GO593_RS10565 (GO593_10565) | rhtC | 2221445..2222065 (+) | 621 | WP_000959259.1 | threonine export protein RhtC | - |
| GO593_RS10570 (GO593_10570) | - | 2222108..2222395 (-) | 288 | WP_001218560.1 | PA4642 family protein | - |
| GO593_RS10575 (GO593_10575) | minE | 2222479..2222751 (-) | 273 | WP_000896934.1 | cell division topological specificity factor MinE | - |
| GO593_RS10580 (GO593_10580) | minD | 2222754..2223566 (-) | 813 | WP_001074362.1 | septum site-determining protein MinD | - |
| GO593_RS10585 (GO593_10585) | minC | 2223637..2224359 (-) | 723 | WP_000763677.1 | septum site-determining protein MinC | - |
| GO593_RS10590 (GO593_10590) | - | 2224481..2225527 (-) | 1047 | WP_001181637.1 | hypothetical protein | - |
| GO593_RS10595 (GO593_10595) | - | 2225544..2226470 (-) | 927 | WP_000100975.1 | acyltransferase | - |
| GO593_RS10600 (GO593_10600) | - | 2226715..2227368 (+) | 654 | WP_001202415.1 | OmpA family protein | - |
| GO593_RS10605 (GO593_10605) | rep | 2227562..2229601 (+) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| GO593_RS10610 (GO593_10610) | dut | 2229627..2230079 (+) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| GO593_RS10615 (GO593_10615) | - | 2230279..2231697 (+) | 1419 | WP_001102833.1 | phosphomannomutase/phosphoglucomutase | - |
| GO593_RS10620 (GO593_10620) | argB | 2231712..2232620 (+) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| GO593_RS10625 (GO593_10625) | - | 2232741..2233523 (+) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| GO593_RS10630 (GO593_10630) | - | 2233632..2234480 (+) | 849 | WP_000336554.1 | class II glutamine amidotransferase | - |
| GO593_RS10635 (GO593_10635) | - | 2234733..2235188 (+) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| GO593_RS10640 (GO593_10640) | - | 2235341..2236408 (+) | 1068 | WP_005144332.1 | hypothetical protein | - |
| GO593_RS10645 (GO593_10645) | - | 2236408..2236731 (+) | 324 | WP_000442584.1 | RnfH family protein | - |
| GO593_RS10650 (GO593_10650) | - | 2236786..2237184 (-) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| GO593_RS10655 (GO593_10655) | fur | 2237296..2237733 (+) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| GO593_RS10660 (GO593_10660) | pilU | 2237803..2238921 (-) | 1119 | WP_000347036.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| GO593_RS10665 (GO593_10665) | pilT | 2238949..2239986 (-) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| GO593_RS10670 (GO593_10670) | - | 2240113..2240805 (+) | 693 | WP_001108520.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| GO593_RS10675 (GO593_10675) | - | 2241006..2244602 (-) | 3597 | WP_000698801.1 | AAA family ATPase | - |
| GO593_RS10680 (GO593_10680) | - | 2244612..2245880 (-) | 1269 | WP_001984248.1 | exonuclease SbcCD subunit D | - |
| GO593_RS10685 (GO593_10685) | - | 2246045..2246518 (+) | 474 | WP_002134289.1 | OsmC family protein | - |
| GO593_RS10690 (GO593_10690) | - | 2246592..2246969 (-) | 378 | WP_001059437.1 | VOC family protein | - |
| GO593_RS10695 (GO593_10695) | - | 2247349..2247801 (+) | 453 | WP_000164154.1 | ABZJ_00895 family protein | - |
| GO593_RS10700 (GO593_10700) | - | 2247890..2248795 (+) | 906 | WP_001039359.1 | TIGR01777 family oxidoreductase | - |
| GO593_RS10705 (GO593_10705) | - | 2248787..2249902 (-) | 1116 | WP_000546700.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| GO593_RS10710 (GO593_10710) | hemB | 2249928..2250941 (-) | 1014 | WP_000222569.1 | porphobilinogen synthase | - |
| GO593_RS10715 (GO593_10715) | - | 2251084..2251581 (+) | 498 | WP_002019577.1 | thioesterase family protein | - |
| GO593_RS10720 (GO593_10720) | - | 2251851..2253002 (+) | 1152 | WP_000128703.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| GO593_RS10725 (GO593_10725) | - | 2253009..2254532 (+) | 1524 | WP_000857095.1 | DHA2 family efflux MFS transporter permease subunit | - |
| GO593_RS10730 (GO593_10730) | ggt | 2254836..2256821 (+) | 1986 | WP_001042928.1 | gamma-glutamyltransferase | - |
| GO593_RS10740 (GO593_10740) | - | 2257522..2258751 (+) | 1230 | WP_002134292.1 | tyrosine-type recombinase/integrase | - |
| GO593_RS10745 (GO593_10745) | - | 2258901..2259527 (+) | 627 | WP_000151565.1 | hypothetical protein | - |
| GO593_RS10750 (GO593_10750) | - | 2259655..2259870 (+) | 216 | WP_000153154.1 | hypothetical protein | - |
| GO593_RS10755 (GO593_10755) | - | 2259873..2260082 (+) | 210 | WP_001016479.1 | helix-turn-helix domain-containing protein | - |
| GO593_RS10760 (GO593_10760) | - | 2260079..2260633 (+) | 555 | WP_000991775.1 | Bro-N domain-containing protein | - |
| GO593_RS10765 (GO593_10765) | - | 2260626..2260994 (+) | 369 | WP_001046480.1 | hypothetical protein | - |
| GO593_RS10770 (GO593_10770) | - | 2261004..2261315 (+) | 312 | WP_000787400.1 | hypothetical protein | - |
| GO593_RS10775 (GO593_10775) | - | 2261430..2261708 (+) | 279 | WP_001064706.1 | hypothetical protein | - |
| GO593_RS10780 (GO593_10780) | - | 2261720..2264185 (+) | 2466 | WP_001022433.1 | DUF927 domain-containing protein | - |
| GO593_RS10785 (GO593_10785) | - | 2264509..2264712 (+) | 204 | WP_001984265.1 | single-stranded DNA-binding protein | - |
| GO593_RS10790 (GO593_10790) | - | 2264849..2266291 (+) | 1443 | WP_000003532.1 | hypothetical protein | - |
| GO593_RS10795 (GO593_10795) | - | 2266634..2267308 (+) | 675 | WP_000560650.1 | DUF3800 domain-containing protein | - |
| GO593_RS10800 (GO593_10800) | - | 2267308..2267496 (+) | 189 | WP_000642900.1 | hypothetical protein | - |
| GO593_RS10805 (GO593_10805) | - | 2267641..2268216 (+) | 576 | WP_000067109.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41905.11 Da Isoelectric Point: 6.6944
>NTDB_id=406496 GO593_RS10660 WP_000347036.1 2237803..2238921(-) (pilU) [Acinetobacter baumannii strain ATCC 19606]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLHSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=406496 GO593_RS10660 WP_000347036.1 2237803..2238921(-) (pilU) [Acinetobacter baumannii strain ATCC 19606]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAATAGTCTTTCAGGCGAAGTAATTGGTCAACTATTACATTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTCGTAGGCGCGACAG
GTACAGGTAAATCCACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCTTCCGATCTCTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGGCAAATTGTTCCAATTTCAAAAAATAGTCTTTCAGGCGAAGTAATTGGTCAACTATTACATTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCGGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTCGTAGGCGCGACAG
GTACAGGTAAATCCACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGTTGCATCATTACTCAGCGTGAAGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACACTACGACAAGCGCCGGATGTGATCTTAATTGGTGAGATCCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCGCTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGTCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAAGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.926 |
100 |
0.772 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.293 |
98.925 |
0.685 |
| pilU | Vibrio cholerae strain A1552 |
53.243 |
99.462 |
0.53 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.197 |
93.011 |
0.392 |