Detailed information NTG0403359

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL188_RS09475
• Genome accession: NZ_CP046359
• Coordinates: 1861600..1862610 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 573
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1856600..1867610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL188_RS09450 (GL188_09605)	-	1856665..1857879 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
GL188_RS09455 (GL188_09610)	-	1858035..1858328 (-)	294	WP_000977366.1	hypothetical protein	-
GL188_RS09460 (GL188_09615)	-	1858491..1858943 (+)	453	WP_000079148.1	universal stress protein	-
GL188_RS09465 (GL188_09620)	-	1858978..1860366 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL188_RS09470 (GL188_09625)	-	1860432..1861394 (+)	963	WP_001124777.1	asparaginase	-
GL188_RS09475 (GL188_09630)	ccpA	1861600..1862610 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL188_RS09480 (GL188_09635)	-	1863035..1863634 (-)	600	WP_000866719.1	response regulator transcription factor	-
GL188_RS09485 (GL188_09640)	-	1863636..1864733 (-)	1098	WP_000893546.1	sensor histidine kinase	-
GL188_RS09490 (GL188_09645)	-	1864733..1865470 (-)	738	WP_000832834.1	ABC transporter permease	-
GL188_RS09495 (GL188_09650)	-	1865472..1866356 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL188_RS09500 (GL188_09655)	-	1866343..1866537 (-)	195	WP_000820180.1	hypothetical protein	-
GL188_RS09505 (GL188_09660)	-	1866534..1866740 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403359 GL188_RS09475 WP_000990607.1 1861600..1862610(-) (ccpA) [Streptococcus pneumoniae strain 573]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403359 GL188_RS09475 WP_000990607.1 1861600..1862610(-) (ccpA) [Streptococcus pneumoniae strain 573]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568