Detailed information NTG0352712

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ES298_RS08505
• Genome accession: NZ_CP038253
• Coordinates: 1678839..1679498 (+)
• Length: 219 a.a.
• NCBI ID: WP_000564991.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1673839..1684498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS08480 (ES298_08940)	-	1674144..1674461 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
ES298_RS08485 (ES298_08945)	-	1674476..1675372 (-)	897	WP_000825665.1	PEP phosphonomutase	-
ES298_RS08490 (ES298_08950)	-	1675369..1676637 (-)	1269	WP_000413337.1	PTS sugar transporter subunit IIC	-
ES298_RS08495 (ES298_08955)	-	1676917..1678095 (+)	1179	WP_000175879.1	ROK family transcriptional regulator	-
ES298_RS08500 (ES298_08960)	-	1678323..1678769 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
ES298_RS08505 (ES298_08965)	cclA/cilC	1678839..1679498 (+)	660	WP_000564991.1	A24 family peptidase	Machinery gene
ES298_RS08510 (ES298_08970)	-	1679550..1680701 (-)	1152	WP_000481750.1	ImmA/IrrE family metallo-endopeptidase	-
ES298_RS08515 (ES298_08975)	-	1680716..1681447 (-)	732	WP_000934018.1	hypothetical protein	-
ES298_RS08520 (ES298_08980)	-	1681673..1681777 (+)	105	Protein_1706	prepilin peptidase	-
ES298_RS08525 (ES298_08985)	trpA	1681749..1682525 (-)	777	WP_001127044.1	tryptophan synthase subunit alpha	-
ES298_RS08530 (ES298_08990)	trpB	1682518..1683741 (-)	1224	WP_000331294.1	tryptophan synthase subunit beta	-
ES298_RS08535 (ES298_08995)	-	1683719..1684318 (-)	600	WP_000169912.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24880.03 Da
• Isoelectric Point: 7.9671

>NTDB_id=352712 ES298_RS08505 WP_000564991.1 1678839..1679498(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901929]
MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=352712 ES298_RS08505 WP_000564991.1 1678839..1679498(+) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901929]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGAA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae D39	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae R6	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.388	100	0.854