Detailed information NTG0315786

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: TFGB2_RS10015
• Genome accession: NZ_CP032429
• Coordinates: 1696726..1697586 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain TFG-B2
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1691726..1702586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TFGB2_RS09995 (TFGB2_01778)	dapD	1692236..1693057 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
TFGB2_RS10000 (TFGB2_01779)	pgi	1693267..1694910 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
TFGB2_RS10010 (TFGB2_01780)	pilG	1695420..1696652 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
TFGB2_RS10015 (TFGB2_01781)	pilD	1696726..1697586 (+)	861	WP_003689814.1	A24 family peptidase	Machinery gene
TFGB2_RS10020 (TFGB2_01782)	coaE	1697583..1698215 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
TFGB2_RS10025 (TFGB2_01783)	-	1698208..1698417 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
TFGB2_RS10030 (TFGB2_01784)	pilF	1698503..1700179 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
TFGB2_RS10045 (TFGB2_01786)	-	1700517..1700963 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
TFGB2_RS10050 (TFGB2_01787)	-	1700967..1701941 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
TFGB2_RS10060 (TFGB2_01788)	rplU	1702165..1702473 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=315786 TFGB2_RS10015 WP_003689814.1 1696726..1697586(+) (pilD) [Neisseria gonorrhoeae strain TFG-B2]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=315786 TFGB2_RS10015 WP_003689814.1 1696726..1697586(+) (pilD) [Neisseria gonorrhoeae strain TFG-B2]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441