Detailed information NTG0309436

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: DZ894_RS25810
• Genome accession: NZ_CP031659
• Coordinates: 5373186..5374523 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PABL012
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5368186..5379523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZ894_RS25785 (DZ894_25785)	pgeF	5368329..5369057 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
DZ894_RS25790 (DZ894_25790)	rluD	5369054..5370016 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
DZ894_RS25795 (DZ894_25795)	-	5370162..5371187 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
DZ894_RS25800 (DZ894_25800)	-	5371344..5371589 (+)	246	WP_003102591.1	PP0621 family protein	-
DZ894_RS25805 (DZ894_25805)	pilS	5371579..5373171 (+)	1593	WP_003119425.1	two-component system sensor histidine kinase PilS	Regulator
DZ894_RS25810 (DZ894_25810)	pilR	5373186..5374523 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
DZ894_RS25815 (DZ894_25815)	thiO	5374569..5375663 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
DZ894_RS25820 (DZ894_25820)	-	5375798..5376307 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
DZ894_RS25825 (DZ894_25825)	-	5376413..5376919 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
DZ894_RS25830 (DZ894_25830)	pilV	5376910..5377467 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
DZ894_RS25835 (DZ894_25835)	pilW	5377464..5378288 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
DZ894_RS25840 (DZ894_25840)	pilX	5378285..5378872 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=309436 DZ894_RS25810 WP_003094694.1 5373186..5374523(+) (pilR) [Pseudomonas aeruginosa strain PABL012]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=309436 DZ894_RS25810 WP_003094694.1 5373186..5374523(+) (pilR) [Pseudomonas aeruginosa strain PABL012]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384