Detailed information NTG0309026

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DZN59_RS09355
• Genome accession: NZ_CP031636
• Coordinates: 1850174..1851397 (+)
• Length: 407 a.a.
• NCBI ID: WP_011285340.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS10826
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1845174..1856397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN59_RS09340 (DZN59_09335)	-	1848313..1849087 (-)	775	Protein_1741	IS30 family transposase	-
DZN59_RS09350 (DZN59_09345)	rlmH	1849483..1849962 (-)	480	WP_002981964.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DZN59_RS09355 (DZN59_09350)	htrA	1850174..1851397 (+)	1224	WP_011285340.1	trypsin-like peptidase domain-containing protein	Regulator
DZN59_RS09360 (DZN59_09355)	spo0J	1851486..1852262 (+)	777	WP_021340715.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42786.41 Da
• Isoelectric Point: 7.3103

>NTDB_id=309026 DZN59_RS09355 WP_011285340.1 1850174..1851397(+) (htrA) [Streptococcus pyogenes strain MGAS10826]
MPSMKYILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide

• Length: 1224 bp

>NTDB_id=309026 DZN59_RS09355 WP_011285340.1 1850174..1851397(+) (htrA) [Streptococcus pyogenes strain MGAS10826]
ATGCCAAGTATGAAATATATCTTAAAATCCTTAAGTATTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGAATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.881	99.263	0.614
htrA	Streptococcus gordonii str. Challis substr. CH1	55.224	98.771	0.545
htrA	Streptococcus mitis NCTC 12261	53.071	100	0.531
htrA	Streptococcus pneumoniae Rx1	53.383	98.034	0.523
htrA	Streptococcus pneumoniae D39	53.383	98.034	0.523
htrA	Streptococcus pneumoniae R6	53.383	98.034	0.523
htrA	Streptococcus pneumoniae TIGR4	53.383	98.034	0.523