Detailed information NTG0305347

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DWB98_RS04870
• Genome accession: NZ_CP031275
• Coordinates: 1049563..1050606 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1044563..1055606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DWB98_RS04845 (DWB98_04855)	-	1045517..1046239 (+)	723	WP_042362406.1	type 1 glutamine amidotransferase	-
DWB98_RS04850 (DWB98_04860)	-	1046442..1047428 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
DWB98_RS04855 (DWB98_04865)	map	1047605..1048357 (+)	753	WP_069796260.1	type I methionyl aminopeptidase	-
DWB98_RS04860 (DWB98_04870)	-	1048462..1048848 (+)	387	WP_042362408.1	hypothetical protein	-
DWB98_RS04865 (DWB98_04875)	liaF	1048865..1049566 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
DWB98_RS04870 (DWB98_04880)	vraS	1049563..1050606 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
DWB98_RS04875 (DWB98_04885)	vraR	1050596..1051225 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
DWB98_RS04880 (DWB98_04890)	-	1051494..1052639 (-)	1146	WP_107543100.1	YihY/virulence factor BrkB family protein	-
DWB98_RS04885 (DWB98_04895)	-	1052995..1053279 (-)	285	WP_042362412.1	hypothetical protein	-
DWB98_RS04890 (DWB98_04900)	-	1053286..1053750 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
DWB98_RS04895 (DWB98_04905)	-	1053885..1054088 (+)	204	WP_017723498.1	DUF1128 family protein	-
DWB98_RS04900 (DWB98_04910)	-	1054106..1055344 (+)	1239	WP_069794719.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=305347 DWB98_RS04870 WP_042362410.1 1049563..1050606(+) (vraS) [Staphylococcus xylosus strain]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=305347 DWB98_RS04870 WP_042362410.1 1049563..1050606(+) (vraS) [Staphylococcus xylosus strain]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCTCTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTGCCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885