Detailed information NTG0030403

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: HSM_RS05520
• Genome accession: NC_010519
• Coordinates: 1227328..1228461 (-)
• Length: 377 a.a.
• NCBI ID: WP_012340255.1
• Uniprot ID: A0A9Q6YYH7
• Organism: Histophilus somni 2336
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1222328..1233461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSM_RS05500 (HSM_1063)	galU	1223706..1224593 (+)	888	WP_012340251.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
HSM_RS05505 (HSM_1064)	-	1224641..1225504 (-)	864	WP_012340252.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
HSM_RS05510 (HSM_1065)	aroB	1225511..1226599 (-)	1089	WP_012340253.1	3-dehydroquinate synthase	-
HSM_RS05515 (HSM_1066)	aroK	1226619..1227146 (-)	528	WP_012340254.1	shikimate kinase AroK	-
HSM_RS05520 (HSM_1067)	comE	1227328..1228461 (-)	1134	WP_012340255.1	type IV pilus secretin PilQ	Machinery gene
HSM_RS05525 (HSM_1068)	-	1228477..1228974 (-)	498	WP_011609266.1	hypothetical protein	-
HSM_RS05530 (HSM_1069)	-	1228978..1229517 (-)	540	WP_012340256.1	PilN domain-containing protein	-
HSM_RS05535 (HSM_1070)	-	1229521..1230306 (-)	786	WP_012340257.1	hypothetical protein	-
HSM_RS05540 (HSM_1071)	-	1230431..1232971 (+)	2541	WP_012340258.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42360.38 Da
• Isoelectric Point: 6.4072

>NTDB_id=30403 HSM_RS05520 WP_012340255.1 1227328..1228461(-) (comE) [Histophilus somni 2336]
MLIKNFLYFFLFLFTVSVELSARDPFDKRQRSIKKETNIQLDTKENLSKSTNEPNLTTTSIKLHYAKAADVMKSLTTGQG
SWLSSNGTFSFDERSNLLLIQDNQETLNALKKLIKEMDQPIEQIAIEARIVTISDENLKELGVRWGIFEPTNNAHHLSGN
LAANGFQHLTEQLNVNFATTATPAGSIALQIAKINDRLLDLELTALERENNVEIIASPRLLTTNKQSASIKQGTEIPYVI
TGKKSDEQKVEFREAVLGLEVTPHISKDNTILLDLIVSQNSPGSRITYGQNEMVSIDKQEINTQVFAQDGETIVLGGVFH
DTITKGVDKVPLLGDIPILKRLFSRESERHQKRELVIFVTPRIIRSEQPNEIIKPLK

Nucleotide

• Length: 1134 bp

>NTDB_id=30403 HSM_RS05520 WP_012340255.1 1227328..1228461(-) (comE) [Histophilus somni 2336]
ATGTTAATTAAAAATTTCTTATATTTCTTTTTGTTCTTATTCACAGTAAGTGTGGAATTATCTGCTAGAGATCCCTTTGA
TAAAAGACAAAGAAGCATAAAAAAAGAGACAAATATACAATTAGATACAAAGGAAAATTTGTCAAAATCGACTAATGAGC
CAAATTTAACGACGACTTCGATCAAATTACATTATGCTAAAGCGGCTGATGTAATGAAATCACTGACTACAGGTCAAGGT
TCATGGCTTTCATCAAATGGAACTTTTAGTTTTGATGAACGAAGTAACTTGCTCTTAATTCAGGATAATCAGGAAACTCT
CAATGCCTTAAAAAAATTAATCAAAGAAATGGATCAACCTATTGAACAAATTGCAATTGAAGCGAGAATTGTAACAATTA
GCGATGAAAATTTAAAAGAATTGGGGGTTCGTTGGGGAATTTTTGAGCCTACAAATAACGCTCATCATCTTTCAGGCAAT
CTAGCAGCAAACGGATTTCAGCATTTAACGGAACAACTTAACGTCAATTTTGCTACTACCGCAACACCTGCAGGTTCTAT
TGCTTTACAAATTGCCAAAATTAATGATCGACTTTTAGACTTAGAACTTACCGCACTTGAACGAGAAAATAATGTAGAAA
TTATTGCAAGCCCTCGTTTACTTACAACGAATAAGCAAAGTGCAAGTATTAAACAAGGAACTGAAATTCCTTATGTTATT
ACCGGCAAGAAATCTGATGAACAGAAAGTAGAGTTTAGAGAAGCAGTTTTAGGATTAGAAGTAACGCCACACATTTCTAA
AGACAATACTATTTTACTGGATCTCATTGTAAGCCAAAACTCCCCTGGAAGTCGTATTACTTATGGGCAAAATGAAATGG
TATCTATTGATAAACAAGAAATTAATACTCAAGTTTTTGCACAAGATGGGGAAACGATTGTGTTGGGTGGCGTATTTCAC
GATACAATCACAAAAGGAGTAGATAAAGTACCGCTGTTAGGAGACATACCTATATTAAAAAGACTGTTCAGCCGTGAAAG
TGAAAGACACCAAAAACGTGAATTAGTCATTTTTGTTACCCCAAGGATCATTCGTTCAGAACAACCTAATGAAATAATAA
AACCATTAAAATAG

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (60-123)

• Bacterial type II and III secretion system protein (Secretin) (205-365)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	74.769	86.207	0.645
comE	Haemophilus influenzae Rd KW20	74.462	86.207	0.642
comE	Glaesserella parasuis strain SC1401	61.587	83.554	0.515
pilQ	Vibrio campbellii strain DS40M4	44.932	96.817	0.435
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	47.205	85.411	0.403
pilQ	Vibrio cholerae strain A1552	47.205	85.411	0.403